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Table 2 Association of KCNJ16 mRNA expression with different variables of thyroid tumor patients

From: Targeting the inward rectifier potassium channel 5.1 in thyroid cancer: artificial intelligence-facilitated molecular docking for drug discovery

Variable

Cases (n = 68(%))

KCNJ16 expression (2−ΔCt)

P-value

Gender

   

 Female

50(74)

0.08296(0.05275, 0.1277)

0.56

 Male

18(26)

0.06787(0.04606, 0.1108)

 

Age/yr

   

 <55

56(82)

0.08515(0.05309, 0.1255)

0.13

 ≥55

12(18)

0.06295(0.01532, 0.1223)

 

Tumor diameter/cm

   

 ≤2

58(85)

0.07784(0.05204, 0.1241)

0.86

 >2

10(15)

0.08093(0.05070, 0.1331)

 

Histological types

   

 Benign

6(9)

0.08436(0.04653, 0.1111)

0.43

 PTCa

36(53)

0.06598(0.04574, 0.1220)

 

 PTMCb

26(38)

0.08296(0.05831, 0.1414)

 

Lymph node metastasis

   

 Yes

41(60)

0.08668(0.04913, 0.1305)

0.58

 No

27(40)

0.06807(0.05294, 0.1219)

 

Vascular/capsular invasion

   

 Yes

28(41)

0.06485(0.04078, 0.1002)

0.02 *

 No

40(59)

0.08949(0.05475, 0.1527)

 

BRAF V600E

   

 Wild type

21(31)

0.08361(0.05431, 0.1176)

0.82

 Mutation

47(69)

0.07322(0.05159, 0.1303)

 

Stage

   

 Stage I

57(84)

0.08232(0.05325, 0.1305)

0.07

 Stage II+III

5(7)

0.02196(0.007871, 0.1285)

 
  1. a: papillary thyroid carcinoma
  2. b: papillary thyroid microcarcinoma
  3. *: Bold fonts indicate statistical significance