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Fig. 5 | BMC Endocrine Disorders

Fig. 5

From: Targeting the inward rectifier potassium channel 5.1 in thyroid cancer: artificial intelligence-facilitated molecular docking for drug discovery

Fig. 5

Target genes expression in clinical samples and DEGs enriched pathways

(A) Individual expression and median expression of TSHR in paratumor and tumor tissue. (B) Individual expression and median expression of KCNJ16 in paratumor and tumor tissue. (C) Individual expression and median expression of SYT1 in paratumor and tumor tissue. (D) The correlation analysis of KCNJ16-TSHR expression and SYT1-TSHR expression of clinical samples. (E) The enriched pathways of DEGs in “high-KCNJ16” group of thyroid cancer patients from TCGA database. (F) The GSEA analysis of listed pathways in ATC patients from GEO database. The running enrichment score from − 0.25 to 0.75. DEG: differentially expressed gene, GSEA: gene set enrichment analysis, ATC: anaplastic thyroid cancer. *: P < 0.05

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BMC Endocrine Disorders

ISSN: 1472-6823

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