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Table 3 Percentage change in diabetes mellitus medication prescription rates from 2004 – 2020 with 95% CI

From: Diabetes mellitus-related hospital admissions and prescriptions of antidiabetic agents in England and Wales: an ecological study

Diabetes mellitus medication

Medication prescription rates in 2004 per 100,000 persons (95% CI)

Medication prescription rates in 2020 per 100,000 persons (95% CI)

% Change from 2004—2020

Average change per year

“Short-acting insulins”

1986.86 (1983.121990.60)

4456.35 (4451.114461.58)

124.3%

7.8%

“Intermediate and long-acting insulins”

6441.32 (6434.74–6447.90)

9013.70 (9006.44–9020.97)

39.9%

2.5%

“Sulphonylureas”

10817.13 (10808.80–10825.46)

13355.52 (13346.89–13364.14)

23.5%

1.5%

“Biguanides”

14937.54 (14927.98–14947.10)

39928.28 (39915.86–39940.71)

167.3%

10.5%

“Other antidiabetics”

2907.30 (2902.79–2911.81)

21203.02(21192.65–21213.39)

629.3%

39.3%

“Treatment of hypoglycaemia”

325.46 (323.94–326.99)

597.39 (595.43–599.34)

83.5%

5.2%

“Diagnostic and monitoring agents for diabetes mellitus”

11792.75 (11784.1011801.40)

12752.60 (12744.1412761.06)

8.1%

0.5%