BMC Endocrine Disorders

Table 3 Results of binary logistic regression analysis

From: Quality of life in patients with primary hyperparathyroidism before and after parathyroidectomy: long term single center experience

Independent variables^a	Univariate analysis			Multivariate analysis
Independent variables^a	p-Value	Odds Ratio	95% Confidence Interval	p-Value	Odds Ratio	95% Confidence Interval
Age, yrs	0.313	0.974	0.926–1.025
Education
Seconday High^b	0.738	0.833	0.287–2.422
Disease duration, weeks	0.49	1.003	0.995–1.012
Baseline Ca²⁺, mmol/L	0.049	0.017	0–0.976	0.119	0.021	0.000–2.693
Baseline p-PTH, pmol/L	0.552	0.990	0.960–1.002
Clinical types of PHPT:
“asymptomatic”
“symptomatic” ^b	0.929	1.048	0.369–2.98
Comorbidities
no	0.929	1.048	0.369–2.98
yes^b
Baseline PC by PHPQoL	0.032	0.969	0.942–0.997	0.127	1.043	0.988–1.101
Baseline MC by PHPQoL	0.001	0.933	0.896–0.972	0.013	0.927	0.874–0.984
Baseline tiredness	0.006	1.03	1.008–1.052	0.185	1.025	0.988–1.063
Baseline mood changes	0.016	1.024	1.004–1.044	0.975	1.000	0.975–1.025
Baseline joint pains	0.203	1.009	0.995–1.022
Baseline weakness^c	0.004	1.025	1.008–1.043
Baseline forgetfulness	0.047	1.016	1–1.031	0.885	1.002	0.980–1.024

^aDependent variable—PHPQoL obtained total score increase (reference category – presence of meaningful QoL improvement in ≥ 9 points)
^bReference category
^cBaseline weakness was excluded from the final model because of high correlations with baseline tiredness (Spearman r = 0.8, p < 0.001)

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