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Table 4 Analysis of clinical indicators stratified according to the serum Hcy concentration

From: Serum homocysteine concentration as a marker for advanced diabetic nephropathy in a cohort of elderly patients

 

Hcy (µmol/L)

P-value

< 12

12–19

> 19

Number of subjects

N = 9,988

 N = 12,565

 N = 7,815

 

VD2 (ng/mL)

1.90 ± 4.01

1.74 ± 3.74

1.43 ± 2.73

< 0.001

VD3 (ng/mL)

14.54 ± 8.08

13.91 ± 7.92

13.07 ± 7.70

< 0.001

VD2 + VD3 (ng/mL)

16.46 ± 8.46

15.63 ± 8.43

14.47 ± 8.15

< 0.001

Urine protein quantitation (g/24 h)

0.66 ± 1.58

1.01 ± 1.90

1.28 ± 1.86

< 0.001

eGFR (mL/min)

88.84 ± 28.07

72.97 ± 26.00

59.01 ± 28.64

< 0.001

Urinary protein/creatinine (mg/mmol)

167.45 ± 678.65

288.48 ± 1,585.37

399.09 ± 1,066.41

< 0.001

  1. Abbreviations: eGFR, estimated glomerular filtration rate; Hcy, homocysteine; N, number; VD, vitamin D