Table 3 Univariate and multivariate analyses of risk factors for DN

Age (years)

0.97 (0.97–0.98)

< 0.001

0.96 (0.94–0.97)

< 0.001

1.07 (1.04–1.10)

< 0.001

Hcy (µmol/L)

1.10 (1.08–1.12)

< 0.001

 Hcy < 12 (µmol/L)

1.00

 Hcy 12–19 (µmol/L)

2.35 (1.86–2.98)

< 0.001

1.92 (1.27–2.92)

0.002

 Hcy > 19 (µmol/L)

5.76 (4.31–7.71)

< 0.001

3.28 (1.81–5.96)

< 0.001

VD2 (ng/mL)

0.94 (0.91–0.97)

<0.001

VD3 (ng/mL)

0.96 (0.95–0.97)

< 0.001

VD2 + VD3 (ng/mL)

0.95 (0.94–0.97)

< 0.001

0.95 (0.94–0.97)

< 0.001

0.97 (0.94–0.99)

0.048

Urine protein quantification (mg/24 h)

108.93 (21.36–555.41)

< 0.001

19.74 (4.38–88.95)

< 0.001

eGFR (mL/min)

0.99 (0.99–0.99)

< 0.001

0.99 (0.98–1.00)

0.002

Urinary protein/creatinine (mg/mmol)

1.00 (1.00–1.00)

< 0.001

1.00 (1.00–1.00)

< 0.001