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Table 3 Pregnancy and infant outcomes in patients with acromegaly

From: Safety of pregnancy in acromegaly patients and maternal and infant outcomes after pregnancy: single-center experience from China and review of the literature

No

Age

ART

PIH

GDM

Medical therapy at pregnancy

Pregnancy

Loss (w)

Delivery

Gestation

Newborn weight (g)

Breastfeeding

1a

37

IVF-ET

No

No

No

No

C/S

NA

3150

NA

1b

42

IVF-ET

No

No

No

No

C/S

38 + 3

2860

NA

2a

24

No

No

No

No

No

SVD

40

NA

NA

2b

26

No

No

No

No

Yesc

Non

Non

Non

Non

3

31

No

No

No

Br

No

C/S

37 + 3

3450

Yes-2 mo

4a

24

No

No

No

No

12

Non

Non

Non

Non

4b

25

No

No

No

No

No

SVD

40 + 1

2900

Yes-2 mo

5

27

OI

No

Yes

No

No

C/S

38

NA

NA

6

29

OI

No

No

No

No

SVD

40

3200

Yes-14 mo

7

30

NA

Noa

No

No

No

C/S

40

NA

NA

8

31

No

Yes (37w)

Nob

No

No

SVD

38 + 6

3250

NA

  1. ART, assisted reproduction therapy; IVF-ET, in vitro fertilization and embryo transfer; OI, ovulation induction; PIH, pregnancy induced hypertension; GDM, gestational diabetes mellitus; Br, Bromocriptine; C/S, caesarean section; SVD, spontaneous vaginal delivery; NA, not available.
  2. a: Hypertension diagnosed before pregnancy
  3. b: Diabetes mellitus diagnosed before pregnancy
  4. c: Induced abortion because of active acromegaly with intense headache.