Safety of pregnancy in acromegaly patients and maternal and infant outcomes after pregnancy: single-center experience from China and review of the literature

Table 2 Treatment and modalities before conception in patients with acromegaly

No	Surgery	Radiotherapy	Medication	Pituitary trophic hormone deficiency	Acromegaly control	Hypertension	DM
1a	Yes	GKRS	Oct Lan	GTD ACTH, TSH	Yes	No	No
1b	Yes	GKRS	No	GTD ACTH, TSH	Yes	No	No
2a	Yes	No	Oct	No	No	No	No
2b	Yes	No	Oct	No	No	No	No
3	Yes	No	Br	No`	No	No	No
4a	Yes	GKRS	Br Pas	No	No	No	No
4b	Yes	GKRS	No	No	Yes	No	No
5	Yes	SFRT	Oct	GTD TSH	Yes	No	No
6	Yes	SFRT	No	GTD	Yes
7	Yes	GKRS	Oct	No	No	Yes	No
8	Yes	No	No	TSH	No	No	Yes

GKRS, gamma knife radiosurgery; SFRT, single-fraction radiotherapy; Oct, octreotide; Lan, lanreotide; Br, bromocriptine; Pas, pasireotide; GTD, gonadotropin deficiency; TSH def, thyroid stimulating hormone deficiency; ACTH def, adrenocorticotropic hormone deficiency.

ISSN: 1472-6823