Table 1 The main laboratory and hormone expression profile
From: Primary bilateral macronodular adrenocortical hyperplasia (PBMAH) patient with ARMC5 mutations
Laboratory test (reference range) | On first admission | One week after right adrenalectomy | Before left adrenalectomy |
|---|---|---|---|
Cortisol (8 a.m.), ng/mL (50–280 ng/mL) | 417 | 269 | 234 |
Cortisol (4 p.m.), ng/mL (20–140 ng/mL) | 320 | 249 | 213 |
Cortisol (12 a.m.), ng/mL (10–120 ng/mL) | 329 | 119 | 169 |
ACTH (8 a.m.), pg/mL (5.08–32.8 pg/mL) | 5.43 | < 1.6 | < 1.6 |
ACTH (4 p.m.), pg/mL (10.7–30.5 pg/mL) | 2.69 | < 1.6 | < 1.6 |
ACTH (12 a.m.), pg/mL (5–15 pg/mL) | 5.70 | < 1.6 | < 1.6 |
24-hour UFC, nmol/24H, 160–1112 nmol/24H | 6318 | 5397 | 2631 |
Orthostatic renin activity, ng/mL/h (0.33–5.15 ng/mL/h) | 1.49 | – | – |
Clinostatic renin activity, ng/mL/h (0.07–1.51 ng/mL/h) | 0.62 | – | – |
WBC, (4–10 × 109/L) | 13.8 | 9.22 | 11.63 |
Hemaglobulin | 158 | 123 | 163 |
Platelet, (100–300 × 109/L)) | 219 | 192 | 247 |
eGFR, ml/min/1.73 m2 | 171.42 | 307.11 | |
Creatinine | 60 | 36.2 | 49.1 |
K+ | 2.24–3.42 | 2.59–3.58 | 3.28 |
BNP | 702.97 | 368.32 | – |