Table 1 Characteristics of the study population (567 patients) with and without chronic low-Aspirin use
Variable | Nonusers (n = 357) | Low-dose Aspirin users (n = 210) | P value |
|---|---|---|---|
Age (years) | 63.91 ± 11.16 | 67.14 ± 9.72 | 0.011 |
Male (%) | 150 (42.0%) | 94 (44.8%) | 0.822 |
BMI (kg/m2) | 24.64 ± 3.40 | 24.55 ± 3.86 | 0.867 |
Medical history (%) | |||
Brain diseases | 42 (11.7) | 90 (42.9) | 0.000 |
Pulmonary nodules | 29 (8.1) | 17 (8.1) | 1.000 |
Hepatobiliary diseases | 53 (14.8) | 29 (13.8) | 0.872 |
Gastric diseases | 35 (9.8) | 8 (3.8) | 0.057 |
Osteoporosis | 60 (16.8) | 30 (14.3) | 0.645 |
Thyroid nodule | 81 (22.7) | 59 (28.1) | 0.288 |
Hypertension | 147 (41.2) | 132 (62.9) | 0.000 |
Medication use (%) | |||
Calcium plus Vit D | 87 (24.3) | 31 (14.7) | 0.037 |
Statins | 143 (40.1) | 174 (82.8) | 0.000a |
Alendronate | 8 (2.2) | 9 (4.2) | 0.316 |
Mecobalamin | 48 (13.4) | 45 (21.4) | 0.062 |
Blood pressure medicine | 109 (30.5) | 112 (53.3) | 0.000 |
NSAIDs | 9 (2.5) | 7 (3.3) | 0.740 |
Acid-inhibitory drugs | 52 (14.6) | 7 (3.3) | 0.001 |
Cardiovascular drugs | 22 (6.2) | 32 (15.2) | 0.008 |