Fig. 7
AKT/AMPK/mTOR pathway was altered in HUVECs from GDM-D and GDM-I. Western analysis showing expression levels of pAKT, AKT, pAMPK, AMPKα, p4EBP1, 4EBP1, pmTOR, mTOR and Histograms displaying the relative pAKT/AKT (A, n = 8 per group), pAMPKα/AMPKα (B, with normal n = 4, GDM-D n = 5, GDM-I, n = 10), pmTOR/mTOR (C, n = 9 per group), p4EBP1/4EBP1(D, n = 9 per group). H-scores of pAKT and pAMPK in immunohistochemistry test (E, F). Representative photographs of immunohistochemistry staining of pAMPKα and pAKT in the indicated groups (H). (∗P < 0.05, ∗∗P < 0.01 compared with normal; #P < 0.05, ##P < 0.01 compared with GDM-D).