Parameters | PHPT group (n = 17) | p, W-test | |
---|---|---|---|
Baseline | After surgery | ||
BMI, kg/m2 | 25.0 [23.3; 26.8] | 25.3 [23.8; 27.5] | 0.004 |
Fasting glucose, mmol/l | 5.10 [4.81; 5.24] | 4.69 [4.48; 5.00] | 0.031 |
2-h glucose OGTT, mmol/l | 5.51 [4.56; 6.48] | 5.48 [4.74; 7.22] | 0.379 |
HbA1c, % | 5.30 [5.10; 5.50] | 5.60 [5.30; 5.80] | 0.001 |
Total cholesterol, mmol/l | 4.89 [4.19; 5.59] | 5.08 [4.5; 5.61] | 0.246 |
LDL cholesterol, mmol/l | 2.90 [2.50; 3.64] | 3.23 [2.4; 3.8] | 0.381 |
HDL cholesterol, mmol/l | 1.34 [1.14; 1.76] | 1.33 [1.15; 1.67] | 0.795 |
Triglycerides, mmol/l | 1.16 [1.02; 1.35] | 1.22 [0.93; 1.63] | 0.278 |
Uric acid, µmol/l | 307 [254; 357] | 260 [238; 352] | 0.044 |
Adiponectin, µg/ml | 8.08 [6.27; 9.71] | 7.10 [3.98; 10.3] | 0.059 |
Leptin, µg/l | 10.8 [4.36; 17.6] | 12.1 [4.09; 24.8] | 0.123 |
M-value, mg/kg/min | 5.48 [4.30; 7.43] | 6.17 [4.56; 6.90] | 0.959 |
AUC C-peptide phase 1 | 63.2 [47.5; 73.5] | 53.9 [44.2; 71.0] | 0.679 |
AUC C-peptide phase 2 | 161 [149; 193] | 169 [139; 196] | 0.737 |
AUC IRI phase 1 | 657 [426; 862] | 501 [339; 768] | 0.163 |
AUC IRI phase 2 | 1121 [917; 1320] | 982 [806; 1375] | 0.044 |
Percent body fat, % | 37.6 [25.8; 41.7] | 31.7 [22.5; 37.1] | 0.266 |
Visceral fat area, cm2 | 88.1 [56.6; 140] | 87.8 [59.7; 141] | 0.149 |