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Table 3 The follow-up laboratory parameters of mineral metabolism in the PHPT group

From: Primary hyperparathyroidism in young patients is associated with metabolic disorders: a prospective comparative study

Parameters

PHPT group (n = 17)

p, W-test

Baseline

After surgery

PTH, pg/ml

138 [106; 210]

38.8 [32.7; 49.2]

 < 0.001

Caadj, mmol/l

2.71 [2.61; 2.91]

2.18 [2.16; 2.24]

 < 0.001

Phosphorus, mmol/l

0.76 [0.72; 0.83]

0.94 [0.87; 1.07]

0.001

Magnesium, mmol/l

0.84 [0.82; 0.86]

0.80 [0.77; 0.84]

0.031

eGFR in CKD-EPI, ml/min/1.73 m2

102 [95; 109]

100 [91; 108]

0.070

ALP, U/l

76.0 [65.0; 108]

42.0 [36.0; 56.0]

0.001

Osteocalcin, ng/ml

46.7 [41.0; 54.6]

17.6 [11.4; 23.2]

 < 0.001

25(OH)D, ng/ml

20.5 [16.6; 22.2]

30.4 [22.2; 36.5]

0.004

  1. Data are presented by medians and interquartile ranges (Median, IQR [25;75]%). W-test: the Wilcoxon signed-rank
  2. PHPT Primary hyperparathyroidism, PTH Parathyroid hormone, Caadj Albumin-adjusted calcium, eGFR Estimated glomerular filtration rate, ALP Alkaline phosphatase, 25(OH)D 25 Hydroxyvitamin D
  3. p < 0.05 was considered statistically significant