Parameters | PHPT group (n = 24) | Control group (n = 20) | p, U-test |
---|---|---|---|
BMI, kg/m2 | 24.6 [22.5; 26.5] | 23.9 [22.7; 25.9] | 0.612 |
Fasting glucose, mmol/l | 5.04 [4.63; 5.23] | 4.83 [4.50; 5.20] | 0.556 |
2-h glucose OGTT, mmol/l | 5.51 [4.78; 6.34] | 4.89 [4.40; 5.74] | 0.260 |
HbA1c, % | 5.30 [5.10; 5.50] | 5.20 [5.10; 5.50] | 0.815 |
Total cholesterol, mmol/l | 4.94 [4.49; 5.41] | 5.18 [4.36; 5.46] | 0.732 |
LDL cholesterol, mmol/l | 3.04 [2.58; 3.69] | 3.39 [2.36; 3.62] | 0.962 |
HDL cholesterol, mmol/l | 1.35 [1.14; 1.75] | 1.53 [1.26; 1.76] | 0.494 |
Triglycerides, mmol/l | 1.13 [0.94; 1.39] | 0.79 [0.63; 1.01] | 0.001 |
Uric acid, µmol/l | 298 [246; 366] | 253 [231; 311] | 0.134 |
Adiponectin, µg/ml | 7.22 [4.56; 8.79] | 7.23 [4.81; 10.8] | 0.849 |
Leptin, µg/l | 12.5 [4.74; 18.8] | 7.09 [6.28; 11.7] | 0.247 |
M-value, mg/kg/min | 5.60 [4.25; 7.45] | 7.90 [7.00; 10.6] | 0.001 |
AUC C-peptide phase 1 | 61.9 [44.4; 73.9] | 37.6 [36.1; 42.6] | < 0.001 |
AUC C-peptide phase 2 | 160 [145; 198] | 132 [115; 175] | 0.019 |
AUC IRI phase 1 | 648 [438; 834] | 294 [259; 384] | < 0.001 |
AUC IRI phase 2 | 1150 [961; 1448] | 760 [657; 1012] | 0.001 |
Percent body fat, % | 31.5 [20.9; 36.2] | 31.2 [25.6; 33.7] | 0.916 |
Visceral fat area, cm2 | 89.9 [61.3; 120] | 88.1 [75.9; 106] | 0.770 |