Table 2 Estimated unadjusted and adjusted odds ratios for PGC as predicted by demographic factors and medical history

PGC^#

Age

1.00 (0.99–1.01)

0.21

Male sex

2.35 (1.49–3.70)

 < 0.001

2.30 (1.39–3.82)

0.001 ^a

History of CVA

0.96 (0.56–1.66)

0.90

Diabetes Mellitus

0.77 (0.45–1.30)

0.33

HLP

0.86 (0.43–1.73)

0.68

Hypertension

1.01 (0.63–1.63)

0.94

Cigarette smoking

6.8 (1.63- 28.40)

 < 0.01

4.47 (1.01–19.78)

0.048^a

Opioid use

2.21 (1.10–4.46)

0.02

1.32 (0.62–2.77)

0.46^a

Men

 Age

1.00 (0.98–1.01)

0.593

 History of CVA

0.63 (0.27–1.44)

0.278

 Diabetes Mellitus

0.59 (0.26–1.34)

0.213

 HLP

1.60 (0.36–7.09)

0.530

 Hypertension

0.83 (0.38–1.80)

0.647

 Cigarette smoking

7.44 (0.99–55.98)

0.051

7.44 (0.99–55.98)

0.051

 Opioid use

1.67 (0.65–4.26)

0.283

Women

 Age

1.02 (1.00–1.03)

0.012

1.02 (1.00–1.036)

0.012

 History of CVA

1.48 (0.71–3.11)

0.293

 Diabetes Mellitus

1.08 (0.54–2.16)

0.818

 HLP

0.080 (0.35–1.85)

0.617

 Hypertension

1.54 (0.82–2.86)

0.173

 Cigarette smoking

2.84 (0.35–23.03)

0.326

 Opioid use

1.97 (0.65–5.97)

0.230

Categorized PGC score^##

 Age

1.00 (0.99–1.01)

0.21

 Male sex

2.34 (1.48–3.69)

 < 0.001

1.72 (1.23–2.39)

0.001 ^b

 History of CVA

0.91 (0.63–1.30)

0.617

 Diabetes Mellitus

1.21 (0.84–1.74)

0.300

 HLP

0.87 (0.54–1.39)

0.566

 Hypertension

0.940 (0.689–1.28)

0.698

 Cigarette smoking

1.84 (1.15- 2.93)

0.010

1.56 (0.97–2.51)

0.062^b

 Opioid use

1.24 (0.85–1.81)

0.247

Men

 Age

1.00 (0.99–1.01)

0.095

1.00 (0.99–1.01)

0.702^c

 History of CVA

0.78 (0.47–1.28)

0.335

 Diabetes Mellitus

1.05 (0.62- 1.75)

0.852

 HLP

0.85 (0.43–1.67)

0.649

 Hypertension

1.07 (0.68–1.66)

0.763

 Cigarette smoking

1.85 (1.088–3.16)

0.023

1.76 (1.02–3.02)

0.039^c

 Opioid use

1.17(0.74- 1.86)

0.484

Women

 Age

1.00 (0.99- 1.01)

0.263

 History of CVA

1.19(0.71–2.01)

0.495

 Diabetes Mellitus

1.61 (0.95–2.72)

0.075

1.61 (0.95–2.72)

0.075

 HLP

0.99 (0.51- 1.92)

0.995

 Hypertension

1.05 (0.66–1.67)

0.804

 Cigarette smoking

0.88 (0.30–2.53)

0.814

 Opioid use

1.958(0.48–1.90)

0.905

Age < 63

 Male sex

1.69 (1.09–2.62)

0.017

2.82 (1.72–4.62)

 < 0.001^d

 Age

1.02 (1.00–1.03)

0.002

1.03 (1.01–1.05)

 < 0.001^d

 History of CVA

1.38 (0.70–2.72)

0.34

 Diabetes Mellitus

1.13 (0.60–2.13)

0.68

 HLP

0.44 (0.17–1.11)

0.083

0.33 (0.13–0.87)

0.025^d

 Hypertension

1.30 (0.78–2.16)

0.309

 Cigarette smoking

1.24 (0.62–2.46)

0.535

Opioid use

1.32 (0.75–2.32)

0.33

Age >  = 63

 Male sex

1.72 (1.13–2.62)

0.011

1.39 (0.88–2.19)

0.152^e

 Age

0.99 (0.96–1.01)

0.42

 History of CVA

0.74 (0.47–1.16)

0.190

 Diabetes Mellitus

1.26 (0.79–2.00)

0.32

 HLP

1.11 (0.63–1.94)

0.703

 Hypertension

0.73 (0.47–1.11)

0.145

 Cigarette smoking

2.57 (1.36–4.85)

0.003

2.31 (1.20–4.42)

0.011^e

 Opioid use

1.18 (0.71–1.96)

0.504

 Cigarette smoking (in men only)

2.94 (1.40–6.18)

0.004

 Cigarette smoking (in women only)

1.05 (0.26–4.23)

0.94