The average 30-minute post-prandial C-peptide predicted diabetic retinopathy progress: a retro-prospective study

BMC Endocrine Disorders

Table 4 Association between C peptide and diabetic retinopathy progression

Variables	Model 1		Model 2
Variables	OR (95% CI)	P value	OR (95% CI)	P value
Baseline FCP, ng/ml	0.91 (0.77–1.08)	0.31	0.92 (0.77–1.09)	0.32
Baseline 30-min PCP, ng/ml	0.91 (0.79–1.04)	0.18	0.91 (0.79–1.05)	0.21
Baseline 120-min PCP, ng/ml	1.02 (0.96–1.08)	0.61	1.02 (0.96–1.08)	0.54
Average FCP, ng/ml	0.86 (0.69–1.06)	0.16	0.86 (0.69–1.07)	0.17
Average 30-min PCP, ng/ml	0.83 (0.72–0.97)	0.018	0.83 (0.71–0.97)	0.018
Average 120-min PCP, ng/ml	0.99 (0.91–1.08)	0.81	0.99 (0.91–1.08)	0.89
Average 30-min PCP increment, ng/ml	0.74 (0.57–0.95)	0.020	0.74 (0.57–0.96)	0.021
Average 120-min PCP increment, ng/ml	1.02 (0.92–1.13)	0.69	1.03 (0.93–1.14)	0.61

Model 1: adjusted by gender, age at baseline, smoking status, alcohol drinking, baseline DR status, hypertension, follow-up period, average levels of waist circumstance, HbA1c, triglyceride and HDL-C; Model 2: further adjusted for diabetes management including insulin therapy and insulin secretagogue

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