Table 2 Clinical characteristics according to diabetic retinopathy progression during follow-up
Variables | No DR progression (n = 458) | DR progression (n = 164) | P value |
|---|---|---|---|
Follow-up period, years | 2.5 (1.5–3.9) | 3.0 (1.9–4.1) | 0.027 |
Gender (men), % | 272 (59.4) | 99 (59.1) | 0.96 |
Average BMI, kg/m2 | 24.5 (22.2–26.9) | 24.9 (23.3–27.2) | 0.12 |
Average WC, cm | 90 (81.5–95.6) | 90.5 (85–98) | 0.22 |
Average SBP, mmHg | 130 (120–140) | 133 (121–143) | 0.11 |
Average DBP, mmHg | 80 (75–85) | 80 (75–85) | 0.97 |
Average HbA1c, % | 8.5 (7.3–9.81) | 8.9 (7.8–10.1) | 0.031 |
Average FPG, mmol/L | 8.30 (6.89–10.2) | 8.86 (7.10–10.9) | 0.10 |
Average 30-minute PPG, mmol/L | 7.45 (5.94–9.19) | 7.43 (5.67–9.53) | 0.90 |
Average 120-minute PPG, mmol/L | 13.3 (10.9–15.8) | 13.75 (11.1–15.8) | 0.31 |
Average FCP, ng/ml | 1.76 (0.97–2.54) | 1.52 (0.84–2.44) | 0.19 |
Average 30-minute PCP, ng/ml | 2.60 (1.37–3.82) | 2.01 (1.19–3.43) | 0.015 |
Average 120-minute PCP, ng/ml | 3.92 (2.20–5.72) | 3.17 (1.76–5.19) | 0.029 |
Average TC, mmol/L | 4.70 (4.06–5.31) | 4.8 (4.36–5.30) | 0.10 |
Average TG, mmol/L | 1.49 (1.02–2.25) | 1.6 (1.08–2.21) | 0.33 |
Average HDL-C, mmol/L | 1.09 (0.96–1.33) | 1.11 (0.98–1.35) | 0.83 |
Average LDL-C, mmol/L | 2.99 (2.51–3.5) | 3.05 (2.51–3.54) | 0.54 |
Average 30-minute PCP increment, ng/ml | 0.64 (0.15–1.35) | 0.41 (0.06–0.99) | 0.015 |
Average 120-minute PCP increment, ng/ml | 1.93 (0.85–3.36) | 1.48 (0.58–2.71) | 0.017 |
DR at baseline, % | 83 (18.1) | 79 (48.2) | < 0.001 |