Table 3 Effect-size estimates of serum thyroid hormones with various stages of DKD
From: Association between thyroid hormones and diabetic kidney disease in Chinese adults
Significant risk factors | Low risk | Moderate risk | High risk | Very high risk |
|---|---|---|---|---|
FT3 (+ 0.2 pg/mL) | Reference | 0.87, 0.81 to 0.93, < 0.001 | 0.79, 0.74 to 0.85, < 0.001 | 0.56, 0.52 to 0.61, < 0.001 |
FT4 (+ 0.2 ng/dL) | Reference | 1.20, 1.06 to 1.38, 0.005 | 1.04, 0.92 to 1.18, 0.491 | 0.82, 0.73 to 0.92, 0.001 |
TSH (+ 0.5 µIU/mL) | Reference | 1.00, 0.99 to 1.00, 0.394 | 1.00, 0.99 to 1.00, 0.378 | 1.00, 1.00 to 1.01, 0.344 |
After balancing age, gender, hypertension, HbA1c, TC, TG and duration of diabetes | ||||
FT3 (+ 0.2 g/mL) | Reference | 0.87, 0.70 to 0.87, 0.006 | 0.78, 0.70 to 0.87, < 0.001 | 0.63, 0.55 to 0.72, < 0.001 |
FT4 (+ 0.2 ng/dL) | Reference | 1.24, 1.04 to 1.50, 0.015 | 1.09, 0.93 to 1.30, 0.277 | 0.93, 0.78 to 1.11, 0.418 |
TSH (+ 0.5 µIU/mL) | Reference | 0.99, 0.97 to 1.02, 0.352 | 0.99, 0.96 to 1.01, 0.264 | 0.99, 0.98 to 1.01, 0.329 |