Table 1 Baseline characteristics of patients stratified by KDIGO categories
From: Association between thyroid hormones and diabetic kidney disease in Chinese adults
Characteristics | Patients with diabetes mellitus | ||||
|---|---|---|---|---|---|
Total (N = 2832) | Low risk (N = 736) | Moderate risk (N = 501) | High risk (N = 578) | Very high risk (N = 1017) | |
Age (years) | 61 (53–69) | 58 (51–66) | 62 (55–70)** | 61 (53–69)** | 62 (54–70)** |
Female, n (%) | 1122 (39.62) | 340 (46.20) | 208 (41.50) | 200 (34.60)** | 374 (36.80)** |
Duration of diabetes (yrs) | 10 (6–20) | 7 (3–12) | 10 (5–16)** | 10 (5–18)** | 14.5 (9–20)** |
Diabetic retinopathy, n (%) | 990 (34.96) | 122 (16.60) | 125 (25.00)** | 217 (37.50)** | 526 (51.70)** |
Hypertension, n (%) | 2045 (72.20) | 256 (64.60) | 350 (71.30)* | 483 (83.60)** | 956 (94.00)** |
SBP (mmHg) | 140 (129–155) | 130 (120–140) | 135 (125–148)** | 140 (130–155)** | 150 (139–165)** |
DBP (mmHg) | 80 (74–90) | 80 (71–85) | 80 (72–88) | 80 (75–90)** | 80 (75–90)** |
BMI (kg/m2) | 26.00 (23.40–28.40) | 26.20 (24.20–29.20) | 26.05 (23.90–29.00) | 25.30 (22.75–28.20) | 25.70 (23.10–28.10) |
HbA1c (%) | 7.1 (6.2–8.6), 0.24 | 7.5 (6.5–9.1) | 7.6 (6.6–9.3) | 7.3 (6.4-9.0) | 6.6 (5.9–7.7)** |
TG (mmol/L) | 1.67 (1.19–2.42), 0.86 | 1.54 (1.11–2.18) | 1.56 (1.14–2.28) | 1.77 (1.25–2.56)** | 1.72 (1.24–2.52)** |
TC (mmol/L) | 4.77 (3.97–5.73), 0.36 | 4.64 (3.93–5.38) | 4.57 (3.77–5.34) | 4.90 (4.10–6.15)** | 4.88 (3.99–6.12)** |
LDL-C (mmol/L) | 2.75 (2.15–3.46), 0.42 | 2.66 (2.12–3.26) | 2.61 (2.03–3.29) | 2.87 (2.22–3.71)** | 2.85 (2.19–3.69)** |
HDL-C (mmol/L) | 1.17 (0.99–1.38), 0.31 | 1.19 (1.01–1.37) | 1.12 (0.97–1.32)** | 1.19 (0.99–1.42) | 1.16 (0.97–1.39) |
eGFR (ml/min/1.73 m²) | 73.6 (36.9–99.4), 0.57 | 100.2 (91.4-108.9) | 91.8 (73.6-103.6)** | 82.6 (64.4–100.0)** | 25.1 (12.2–39.7)** |
UACR (mg/g) | 309.06 (22.96-2182.22), 3.40 | 9.24 (4.96–15.91) | 75.83 (39.50-148.20)** | 957.54 (399.50-2444.80)** | 2251.14 (869.76-4418.82)** |
sALB (mg/L) | 37.9 (33.3–41.8), 0.21 | 41.2 (38.2–44.2) | 40.2 (37.5–43.5)** | 36.0 (30.4–40.4)** | 34.3 (28.8–38.5)** |
T3 (ng/mL) | 0.90 (0.77–1.04), 0.34 | 0.98 (0.85–1.09) | 0.94 (0.81–1.08) | 0.91 (0.79–1.07)** | 0.83 (0.70–0.96)** |
T4 (µg/dL) | 8.00 (6.70–9.20), 0.25 | 8.27 (7.10–9.20) | 8.20 (7.00-9.30) | 7.79 (6.60–8.98)** | 7.90 (6.50–9.20)* |
FT3 (pg/mL) | 2.73 (2.43–3.02), 0.18 | 2.95 (2.71–3.20) | 2.86 (2.62–3.07)** | 2.76 (2.50–3.05)** | 2.45 (2.19–2.70)** |
FT4 (ng/dL) | 1.15 (1.02–1.28), 0.20 | 1.18 (1.06–1.31) | 1.22 (1.07–1.34)* | 1.17 (1.03–1.30) | 1.10 (0.98–1.23)** |
TSH (µIU/mL) | 1.91 (1.25–3.32), 2.54 | 1.70 (1.10–2.65) | 1.61 (1.09–2.53) | 2.01 (1.24–3.24)** | 2.24 (1.46–4.11)** |