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Table 1 Endocrinological work-up at diagnosis

From: Ectopic sphenoidal ACTH-secreting adenoma revealed by 11C Methionine PET scan: case report

Parameter (Units)

Results

Normal range

Morning cortisol (nmol/l)

669

130–500

Morning ACTH (ng/l)

89

5–49

TSH (mU/l)

0.78

0.27–4.2

Free T4 (pmol/l)

16.8

12–22

IGF-1 (μg/l)

148

102–267

LH (U/l)

3.9

1–95

FSH (U/l)

11.9

1.7–134

Oestradiol (ng/l)

23

12–398

Total testosterone (nmol/l)

2.94

0.27–1.7

DHEA-Sulfate (μmol/l)

14.4

1–7

Prolactin (μg/l)

12

5–23

24 h urinary free cortisol on three different collections (μg/24 h)

86.0, 99.3 and 131.0

< 40

Morning cortisol after 1 mg DXM (nmol/l)

369

< 50

Morning cortisol after Liddle test (nmol/l)

911

< 50

  1. The Liddle test was performed by giving 0.5 mg dexamethasone every 6 hours for 48 hours
  2. ACTH adrenocorticotropic hormone, TSH thyroid-stimulating hormone, IGF-1 insulin-like growth factor 1, LH luteinizing hormone, FSH follicle-stimulating hormone, DHEA Dehydroepiandrosterone, DXM dexamethasone