Variable | Curcumin (n = 27) Mean (SD*) | Placebo (n = 27) Mean (SD*) | Mean Difference (95% Confidence Interval) | P-value |
---|---|---|---|---|
Fasting blood sugar (mg/dl) | Â | Â | Â | |
Before intervention | 93.92 (9.12) | 91.33 (9.40) | 2.59 (-2.52 to 7.70) | 0.314†|
After intervention | 90.38 (10.69) | 95.22 (11.226) | -6.24 (-11.73 to -0.76) | 0.027‡ |
Intra-group comparison (P-value* *) | 0.144 | 0.037 | Â | Â |
Triglyceride (mg/dl) | Â | Â | Â | |
Before intervention | 110.81 (47.11) | 137.19 (43.20) | -26.38 (-51.29 to -1.47) | 0.038†|
After intervention | 128.02 (6.13) | 136.27 (6.00) | -8.25 (-25.85 to 9.35) | 0.351‡ |
Intra-group comparison (P-value* *) | 0.214 | 0.202 | Â | Â |
Cholesterol (mg/dl) | Â | Â | Â | |
Before intervention | 158.46 (32.94) | 162.59 (34.97) | -4.13 (-22.88 to 14.62) | 0.660†|
After intervention | 165.85 (37.69) | 174.19 (40.93) | -6.28 (-26.13 to 13.57) | 0.528 |
Intra-group comparison (P-value* *) | 0.167 | 0.228 | Â | Â |
LDL-C (mg/dl) | Â | Â | Â | Â |
Before intervention | 88.77 (25.33) | 91.11 (27.99) | -2.342 (-17.08 to 12.40) | 0.751†|
After intervention | 89.96 (30.92) | 105.70 (29.33) | -14.81 (-30.52 to 0.91) | 0.064‡ |
Intra-group comparison (P-value* *) | 0.783 | 0.070 | Â | Â |
HDL-C (mg/dl) | Â | Â | Â | Â |
Before intervention | 50.12 (10.89) | 51.56 (9.74) | -1.44 (-7.13 to 4.25) | 0.614†|
After intervention | 53.77 (13.15) | 51.56 (9.74) | 3.22 (-3.04 to 9.48) | 0.306‡ |
Intra-group comparison (P-value* *) | 0.198 | 0.873 | Â | Â |
Fasting Insulin (mg/dl) | Â | Â | Â | Â |
Before intervention | 12.54 (7.56) | 9.76 (7.25) | - | 0.135§ |
After intervention | 9.50 (7.02) | 10.11 (9.30) | - | 0.929§ |
Intra-group comparison (P-value††) | 0.005 | 0.760 |  |  |
HOMA-IR | Â | Â | Â | Â |
Before intervention | 2.88 (1.99) | 2.16 (1.43) |  | 0.229§ |
After intervention | 2.11 (1.79 ) | 2.40 (2.11) |  | 0.736§ |
Intra-group comparison (P-value††) | 0.005 | 0.792 |  |  |
Testosterone (After intervention) (ng/dl) | 0.64 (0.39) | 0.77 (0.36) | - | 0.133§ |
SHBG¥ (After intervention) (µg/dl) | 57.11 (38.57) | 60.67 (40.87) | - | 0.682§ |