Table 1 Characteristics of included studies
Study | Year of publication | Sample size | Country | Design | Type of surgery | Medical therapy | Follow-up(Months) | Baseline mean BMI(kg/m2) | Definition of diabtes Remission |
|---|---|---|---|---|---|---|---|---|---|
Daniel H et al | 2020 | 57 | America | Randomized Controlled Trial | RYGB(28%), LSG(62%) or LAGB(10%) | Medical weight management | 36 | 32.8 (bariatric surgery) 32.0 (medical therapy) | Not reported |
Keong C et al | 2017 | 41 | America | Randomized Controlled Trial | RYGB | Intensive medical management | 41 | 32.9 | Blood HbA1c < 6.5% (48 mmol/mol) or < 6% (42 mmol/mol) without any antihyperglycemic medication for at least 1-year duration, respectively |
Wenhuan F et al | 2018 | 40 | China | Retrospective cohort study | RYGB | Weight management and antidiabetic agents | 12 | 33.3 (bariatric surgery) 32.1 (medical therapy) | T2DM required HbA1c less than 6.0% and fasting blood glucose (FBG) less than 5.6 mmol/L, with no use of antidiabetic agents for 1 year |
Chih-Cheng H et al | 2015 | 351 | China | Retrospective cohort study | LSG(36.5%) or GB(63.5%) | Medical treatment | 60 | 31.0 (bariatric surgery) 29.1 (medical therapy) | HbA1c < 6.0% and 6.0%-6.5% of total hemoglobin [Hb; to convert to proportion of total Hb, multiply by 0.01], respectively, for those who were exempted from any antidiabetic drugs for 5 years |
Mohit B et al | 2017 | 70 | India | Prospective study | RYGB | GLP-1 | 12 | 34.17 (bariatric surgery) 32.67 (GLP-1) 31.33(SGLT2) | Not reported |
John M et al | 2014 | 51 | Australlia | Randomized Controlled Trial | LAGB | Multidisciplinary Diabetes Care | 24 | 29.0 (bariatric surgery) 29.0 (medical therapy) | serum glucose values were ≤ 125 mg/dL and HbA1c ≤ 6.0%, on free diet and with no antidiabetic medical therapy, controlled when, under the same conditions, HbA1c was ≤ 7.0%, and improved when preoperative HbA1c was steadily reduced by at least 1% with less antidiabetic therapy |
Bruno G et al | 2012 | 36 | America | Retrospective cohort study | DJB | standard medical care | 12 | 26.1 (bariatric surgery) 26.3 (medical therapy) | Not reported |