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Table 1 Baseline characteristics and details of BIPSS, pituitary imaging and surgical findings

From: Comparison of the preoperative diagnostic accuracy of BIPSS versus MRI for Cushing disease: a single-centre experience

 

BIPSS

MRI

Surgery

% Females

79.3

79.3

81.5

Mean UFC (SD) in nmol/24 h

2284.5 (1223.8)

2284.5 (1223.8)

2287.8 (1251.2)

Mean ACTH (SD) in pmol (8 AM)

23.5 (14.7)

23.5 (14.7)

23.5 (15.1)

Mean ACTH (SD) in pmol (4 PM)

18.2 (11.6)

18.2 (11.6)

17.6 (11.6)

Mean ACTH (SD) in pmol (12 AM)

17.7 (10.7)

17.7 (10.7)

17.7 (11.1)

Mean cortisol (SD) in pmol/24 h after LDDST

20.6 (18.1)

20.6 (18.1)

19.5 (17.8)

Mean cortisol (SD) in pmol/24 h after HDDST

14.8 (14.3)

14.8 (14.3)

13.7 (14.3)

% Right

65.5

34.5

37.0

Mean ratio (SD) of IPS/P before stimulation

12.3 (12.6)

12.3 (12.6)

12.6 (12.9)

Mean ratio (SD) of IPS/P after stimulation (5 min)

10.5 (9.3)

10.5 (9.3)

10.8 (9.3)

Mean ratio (SD) of IPS/P after stimulation (10 min)

7.1 (6.2)

7.1 (6.2)

7.3 (6.2)

Size of pituitary adenoma ≤ 6 mm

15

15

15

  1. ACTH Adrenocorticotropic hormone, LDDST Low-dose dexamethasone suppression test, HDDST High-dose dexamethasone suppression test, UFC Urinary free cortisol, BIPSS Bilateral inferior petrosal sinus sampling, MRI Magnetic resonance imaging, IPS Inferior petrosal sinuses, P Periphery