Table 3 Lipid and glucose metabolism parameters in euthyroid and subclinical hypothyroidism postmenopausal women, before and after MHT

TG(mmol/L)

 Before MHT

1.07 (0.78, 1.51)

1.05 (0.87, 1.41)

0.84 (0.77, 1.90)

0.735

0.693

 After MHT

1.00 (0.67, 1.36)

0.89 (0.75, 1.17)

1.02 (0.64, 1.44)

0.834

0.659

 t/Z

2.860

2.657

0.632

 p value^b

0.004

0.008

0.528

TC(mmol/L)

 Before MHT

5.19 (4.61, 5.81)

5.27 (4.67, 5.84)

4.93 (4.32, 5.61)

1.484

0.476

 After MHT

5.07 (4.44, 5.64)

4.76 (4.16, 5.35)

4.70 (4.18, 5.81)

5.332

0.070

 t/Z

3.892

2.691

0.109

 p value^b

0.000

0.007

0.913

HDL-C(mmol/L)

 Before MHT

1.47 (1.26, 1.72)

1.44 (1.26, 1.72)

1.47 (1.15, 1.88)

0.141

0.932

 After MHT

1.44 (1.25, 1.70)

1.46 (1.26, 1.58)

1.41 (1.24, 1.72)

0.150

0.928

 t/Z

0.895

0.327

0.150

 p value^b

0.371

0.745

0.883

LDL-C(mmol/L)

 Before MHT

2.88 (2.44, 3.38)

2.91 (2.42, 3.62)

2.54 (1.94, 3.03)

4.685

0.096

 After MHT

2.86 (2.41, 3.34)

2.59 (2.35, 3.15)

2.64 (2.16, 3.47)

4.034

0.133

 t/Z

0.817

0.974

1.459

 p value^b

0.414

0.330

0.145

FPG (mmol/L)

 Before MHT

5.26 (4.97, 5.62)

5.26 (4.89, 5.56)

5.18 (4.93, 5.49)

1.175

0.556

 After MHT

5.09 (4.85, 5.35)

5.12 (4.87, 5.36)

4.99 (4.57, 5.37)

1.669

0.434

 t/Z

5.512

0.711

1.034

 p value^b

0.000

0.477

0.301

FINS (μU/ml)

 Before MHT

5.40 (4.10, 7.20)

5.60 (3.90, 8.00)

6.15 (3.70, 6.88)

0.086

0.958

 After MHT

4.80 (3.60, 6.80)

5.10 (3.90, 6.90)

4.85 (3.85, 6.58)

0.874

0.646

 t/Z

3.816

1.728

0.653

 p value^b

0.000

0.084

0.513

HOMA-IR

 Before MHT

1.33 (0.94, 1.77)

1.30 (0.88, 1.97)

1.38 (0.88, 1.60)

0.018

0.991

 After MHT

1.08 (0.78, 1.55)

1.19 (0.86, 1.59)

1.13 (0.78, 1.52)

1.076

0.584

 t/Z

4.442

1.806

0.992

 p value^b

0.000

0.071

0.338