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Table 1 Scores of steatosis, body weight, liver TNF-α and serum endotoxin in different groups

From: α-NETA down-regulates CMKLR1 mRNA expression in ileum and prevents body weight gains collaborating with ERK inhibitor PD98059 in turn to alleviate hepatic steatosis in HFD-induced obese mice but no impact on ileal mucosal integrity and steatohepatitis progression

Group

Body weight

Score of steatosis

TNF-α (pg/mg)

Endotoxin (EU/ml)

HFD

37.90 ± 3.00

3.78 ± 0.44

3.04 ± 0.12

0.55 ± 0.48

NETA

33.22 ± 1.9 a

3.50 ± 0.65

2.74 ± 0.40

0.07 ± 0.22

PD

37.30 ± 4.05

3.90 ± 0.32

2.10 ± 0.74

-0.02 ± 0.05

PD + NETA

31.20 ± 1.74 a

2.73 ± 0.65a

2.38 ± 0.73

-0.00 ± 0.08

ND

24.47 ± 0.50 b

0 ± 0

1.40 ± 0.20c

0.04 ± 0.12

  1. aP < 0.05 vs group HFD
  2. bP < 0.01 vs group HFD
  3. cP < 0.001 vs group HFD