Table 3 Comparison of iron-related parameters, BMD and TBS between pancreatic iron overload and no-iron overload groups
|  | Male (n = 26) | Female (n = 15) | ||||
|---|---|---|---|---|---|---|
No iron overload (n = 16) | iron overload (n = 10) | p | No iron overload (n = 10) | iron overload (n = 5) | p | |
Age, mean (SD), years | 44.13 (11.70) | 43.90 (14.75) | 0.966 | 51.00 (11.99) | 58.80 (15.74) | 0.302 |
Men aged 50 years or above/Women with postmenopause, n(%) | 5 (31.3) | 3 (30.0) | 1.000 | 5 (50.0) | 3 (60.0) | 0.573 |
BMI, mean (SD), (kg/m2) | 23.34 (2.63) | 23.20 (2.64) | 0.898 | 23.69 (3.79) | 21.34 (3.72) | 0.276 |
Serum ferritin (ng/mL), median (IQR) | 1080.63 (515.52) | 2875.63 (2082.68) | 0.045 | 1619.67 (1103.58) | 2315.75 (2246.10) | 0.457 |
Serum iron (μg /dL), mean (SD) | 146.53 (55.14) | 221.42 (101.30) | 0.024 | 178.34 (86.06) | 147.75 (86.43) | 0.560 |
Liver T2*-value (ms), median (IQR) | 7.75 (8.10) | 2.00 (1.30) | 0.001 | 4.85 (4.20) | 2.00 (4.50) | 0.440 |
Pancreatic T2*-value (ms), median (IQR) | 43.00 (12.10) | 7.65 (5.20) | 0.000 | 37.60 (15.3) | 7.60 (12.40) | 0.001 |
BMD (g/cm2), mean (SD) | ||||||
 Lumbar spine | 1.14 (0.16) | 0.98 (0.12) | 0.012 | 1.12 (0.14) | 1.01 (0.16) | 0.179 |
 Femoral neck | 0.94 (0.15) | 0.91 (0.08) | 0.646 | 0.99 (0.13) | 0.79 (0.08) | 0.011 |
 Total hip | 0.97 (0.16) | 0.93 (0.11) | 0.503 | 1.07 (0.11) | 0.79 (0.10) | 0.000 |
T-score, mean (SD) | ||||||
 Lumbar spine | 0.36 (1.32) | −0.92 (0.95) | 0.014 | 0.00 (1.18) | −0.95 (1.26) | 0.172 |
 Femoral neck | −0.29 (1.22) | −0.49 (0.63) | 0.647 | 0.43 (1.10) | −1.15 (0.69) | 0.012 |
 Total hip | −0.11 (1.26) | − 0.44 (0.85) | 0.477 | 0.72 (0.82) | −1.42 (0.77) | 0.000 |
Z-score, mean (SD) | ||||||
 Lumbar spine | 0.68 (1.44) | −0.64 (0.89) | 0.016 | 0.86 (1.14) | 0.49 (0.95) | 0.550 |
 Femoral neck | 0.18 (1.35) | −0.05 (0.70) | 0.623 | 1.18 (1.19) | 0.09 (1.14) | 0.113 |
 Total hip | 0.03 (1.29) | −0.31 (0.84) | 0.480 | 1.22 (0.81) | −0.44 (0.91) | 0.003 |
Abnormal bone mass, n (%) | ||||||
 Lumbar spine | 0 (0.0) | 2 (20.0) | 0.138 | 2 (20.0) | 3 (60.0) | 0.251 |
 Femoral neck | 1 (6.3) | 1 (10.0) | 1.000 | 0 (0.0) | 2 (40.0) | 0.095 |
 Total hip | 1 (6.3) | 1 (10.0) | 1.000 | 0 (0.0) | 3 (60.0) | 0.022 |
TBS | ||||||
 Lumbar spine, mean (SD) | 1.35 (0.10) | 1.34 (0.08) | 0.614 | 1.32 (0.11) | 1.29 (0.11) | 0.601 |
 Abnormal microarchitecture, n (%) | 5 (31.3) | 6 (60.0) | 0.228 | 5 (50.0) | 3 (60.0) | 1.000 |