Table 1 Patient characteristics
Characteristics | Value |
|---|---|
Age (years), mean (SD) | 47.54 (13.57) |
Sex, n (%) | |
 Male | 26 (63.4) |
   ≥ 50 years | 8 (30.8) |
 Female | 15 (36.6) |
  Postmenopause | 8 (53.3) |
BMI (kg/m2), mean (SD) | 23.15 (3.04) |
Serum ferritin (ng/mL), median (IQR) | 1500.00 (1288.00) |
Serum iron (μg/dL), mean (SD) | 172.09 (81.41) |
Liver T2*-value (ms), median (IQR) | 4.80 (5.80) |
 No-mild iron overload (T2* ≥ 3.8 ms), n (%) | 22 (53.7) |
 Moderate-severe iron overload (T2* < 3.8 ms), n (%) | 19 (46.3) |
Pancreatic T2*-value (ms), median (IQR) | 35.20 (24.80) |
 No iron overload (T2* ≥ 21 ms), n (%) | 31 (75.6) |
 Iron overload (T2* < 21 ms), n (%) | 10 (24.4) |
Primary disease, n. (%) | |
 Myelodysplastic syndrome | 13 (31.7) |
 Aplastic anemia | 14 (34.1) |
 Hereditary hemochromatosis | 6 (14.6) |
 β-thalassemia | 5 (12.2) |
 Myelofibrosis | 1 (2.4) |
 Hereditary elliptocytosis | 1 (2.4) |
 Hereditary spherocytosis | 1 (2.4) |
LS | |
 BMD (g/cm2), mean (SD) | 1.08 (0.16) |
 T-score, mean (SD) | −0.20 (1.29) |
 Z-score, mean (SD) | 0.38 (1.30) |
 Osteopenia, n (%) | 6 (14.6) |
 Osteoporosis, n (%) | 1 (2.4) |
 TBS, mean (SD) | 1.33 (0.10) |
 Partially degraded microarchitecture, n (%) | 13 (31.7) |
 Degraded microarchitecture, n (%) | 6 (14.6) |
FN | |
 BMD (g/cm2), mean (SD) | 0.91 (0.12) |
 T-score, mean (SD) | − 0.39 (0.95) |
 Z-score, mean (SD) | 0.13 (0.91) |
 Osteopenia, n (%) | 4 (9.8) |
 Osteoporosis, n (%) | 0 (0) |
TH | |
 BMD (g/cm2), mean (SD) | 0.95 (0.13) |
 T-score, mean (SD) | −0.29 (1.00) |
 Z-score, mean (SD) | 0.03 (0.99) |
 Osteopenia, n (%) | 5 (12.2) |
 Osteoporosis, n (%) | 0 (0) |
Abnormal bone mass, n (%) | 9 (22.0) |
Abnormal microarchitecture, n (%) | 19 (46.3) |