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Table 2 Clinical pathologic characteristics of the cohort

From: Comparing the efficacy of thyroglobulin and thyroglobulin/ thyroid-stimulating hormone ratio models in predicting a successful response to radioactive iodine therapy

 

Level

Overall(1642)

ER(787)

NER(855)

P-value

Age*

 

43.69 (11.50)

43.36 (11.11)

44.00 (11.86)

0.255

Gender (%)

Male

480 (29.2)

169 (21.5)

311 (36.4)

 < 0.001

Female

1162 (70.8)

618 (78.5)

544 (63.6)

 

Pathology type (%)

Papillary carcinoma

1633 (99.5)

784 (99.6)

849 (99.3)

0.586

Follicular carcinoma

9 (0.5)

3 (0.4)

6 (0.7)

 

Capsular invasion (%)

No

1145 (69.7)

562 (71.4)

583 (68.2)

0.172

Yes

497 (30.3)

225 (28.6)

272 (31.8)

 

Metastasis number #

 

3 [2, 7]

3 [1, 5]

4 [2, 8]

 < 0.001

Benign lesion (%)

No

696 (42.4)

305 (38.8)

391 (45.7)

0.005

Yes

946 (57.6)

482 (61.2)

464 (54.3)

 

TNM tumor stage (%)

I

1382 (84.2)

670 (85.1)

712 (83.3)

0.336

II-III

260 (15.8)

117 (14.9)

143 (16.7)

 

ATA risk stratification (%)

Low risk

402 (24.5)

303 (38.5)

99 (11.6)

 < 0.001

Intermediate-high risk

1240 (75.5)

484 (61.5)

756 (88.4)

 

Tg (ng/mL) #

 

2.2 [0.6,7.1]

0.9 [0.2, 2.2]

5.7 [2.0, 16.7]

 < 0.001

Tg/TSH (ng/mIU) #

 

24.7 [5.8,83.7]

9.7 [2.3, 25.4]

64.8 [20.3, 192.6]

 < 0.001

  1. TSH Thyroid stimulating hormone, Tg Thyroglobulin, TNM stage Tumor-node-metastasis stage of patients, ER Excellent response, NER Non-excellent response
  2. (%), number (percentage); *, (mean (standard deviation); #, median [first quartile, third quartile]
  3. Statistical tests: (%), the chi-square test; *, the student t-test; #, the Mann–Whitney U test. Statistical significance: p < 0.05