Modulatory activity of testosterone on growth pattern and IGF-1 levels in vanishing testis syndrome: a case report during 15 years of follow-up

Table 1 Patient’s relevant clinical data during the 15 years of follow-up

Date	Age yrs	Bone Age	Height cm	Height SDS	Height velocity SDS	Weight SDS	IGF-I ng/ml	IGF SDS	T ng/ml	Pubertal stage	Therapy
28/06/91	2.4	-	93	0.78	-	0.2	36	-0.75	< 0.2	Ph0 G0	-
19/06/92	3.38	-	102	0.98	0.9	0.6	50	-0.53	< 0.2	-	-
03/07/96	7.42	-	126.6	0.57	-0.2	-0.2	49	-0.96	< 0.2	Ph1 G1	-
19/06/98	9.38	-	136	0.28	-0.9	0.4	65	-0.81	< 0.2	-	TPr 2.5 mg die
23/04/99	10.22	10.5	141.8	0.80	2.4	0.4	151	0.02	0.8	-	TPr 5 mg die
24/09/00	11.64	11.6	151.7	1.01	2.8	0.2	336	0.47	0.2	-	TUn 20 mg die
06/12/01	12.84	13	158.5	0.65	0.4	2.0	236	-0.14	0.37	Ph2 G2	TUn 40 mg die
11/06/02	13.36	13.5	161.6	0.58	-0.7	0.9	287	0.17	0.37	Ph3 G2	TUn 40 mg die
05/09/03	14.59	14.7	168.4	0.53	-2.9	1.1	375	0.71	0.6	Ph3 G3	TUn 40 mg die
16/07/04	15.45	15.6	173.7	0.46	0.3	1.2	379	0.74	2.2	-	TE ½ fl 21 days
14/06/05	16.36	16.5	176.6	0.46	0.3	1.2	352	0.57	2.96	Ph4 G4	TE 1 fl 21 days
12/06/06	17.36	17.5	177.9	0.51	0.1	1.4	405	0.9	7.6	Ph5 G5	T Gel daily

Legend yrs years, bone age (Greulich-Pyle calculated), SDS standard deviation score, T serum total testosterone, TPr testosterone propionate, TUn testosterone undecanoate, TE testosterone esters, T Gel testosterone gel

ISSN: 1472-6823