Table 3 Preoperative factors associated with the “remission” DM after adrenalectomy in PA patients
From: Recovery from diabetes mellitus in primary aldosteronism patients after adrenalectomy
Factors | Univariate logistic regression | Multivariate logistic regression | ||
|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | |
Age (years) | 1.118 (1.029–1.215) | 0.008 | 0.923 (0.724–1.177) | 0.517 |
Gender (female/male) | 2.333 (0.435–12.530) | 0.323 | ||
BMI (kg/m2) | 1.057 (0.829–1.347) | 0.656 | ||
Duration of hypertension (months) | 1.007 (0.997–1.018) | 0.180 | ||
Duration of DM (months) | 1.012 (0.996–1.028) | 0.144 | ||
Order of hypertension and DM (hypertension-DM/DM-hypertension) | 0.571 (0.106–3.095) | 0.516 | ||
Hemoglobin (g/L) | 0.960 (0.909–1.014) | 0.148 | ||
Red blood cell (1012/L) | 0.143 (0.025–0.799) | 0.027 | 0.002 (0-5.368) | 0.123 |
Platelet (109/L) | 1.001 (0.988–1.013) | 0.933 | ||
ALP (IU/L) | 0.996 (0.964–1.030) | 0.832 | ||
Serum creatinine (µmol/L) | 1.009 (0.972–1.046) | 0.646 | ||
eGFR (mL/min/1.73 m2) | 0.862 (0.761–0.976) | 0.019 | 0.682 (0.417–1.115) | 0.127 |
BUN (mmol/L) | 1.032 (0.652–1.634) | 0.894 | ||
Concentration of urinary K (mmol/L) | 1.085 (0.985–1.195) | 0.098 | 1.150 (0.949–1.393) | 0.154 |
Concentration of urinary Na (mmol/L) | 0.994 (0.973–1.015) | 0.573 | ||
Concentration of urinary Cl (mmol/L) | 1.001 (0.978–1.025) | 0.912 | ||
Concentration of urinary Ca (mmol/L) | 1.541 (0.738–3.219) | 0.249 | ||
Concentration of urinary Mg (mmol/L) | 5.103 (0.835–31.172) | 0.078 | 108.200 (1.526-7671.118) | 0.031 |
Concentration of urinary P (mmol/L) | 0.942 (0.796–1.115) | 0.487 | ||
24 h urinary K (mmol/24 h) | 1.083 (0.995–1.179) | 0.064 | 1.215 (1.001–1.476) | 0.049 |
24 h urinary Na (mmol/24 h) | 1.010 (0.994–1.026) | 0.233 | ||
24 h urinary Cl (mmol/24 h) | 1.011 (0.993–1.030) | 0.223 | ||
24 h urinary Ca (mmol/24 h) | 1.385 (0.768–2.497) | 0.279 | ||
24 h urinary Mg (mmol/24 h) | 2.738 (0.795–9.431) | 0.110 | ||
24 h urinary P (mmol/24 h) | 1.080 (0.880–1.326) | 0.461 | ||
ALD (lying position) (ng/dL) | 0.991 (0.927–1.060) | 0.794 | ||
ALD (standing position) (ng/dL) | 0.996 (0.933–1.063) | 0.895 | ||
ARR (lying position) | 1.000 (0.998–1.001) | 0.680 | ||
ARR (standing position) | 1.000 (0.999–1.001) | 0.877 | ||
PTC8 (Cortisol) (nmol/L) | 1.001 (0.997–1.006) | 0.555 | ||
PTC0 (Cortisol) (nmol/L) | 1.022 (0.991–1.053) | 0.162 | ||
ACTH (ng/L) | 1.007 (0.967–1.049) | 0.729 | ||
Total 24 h UFC (µg/24 h) | 1.005 (0.985–1.025) | 0.653 | ||
Fasting blood glucose before surgery (mmol/L) | 1.173 (0.854–1.611) | 0.325 | 1.419 (0.656–3.066) | 0.374 |
HbA1C before surgery (%) | 0.855 (0.488–1.497) | 0.583 | ||