Table 2 Preoperative factors associated with the “remission” or “improved” DM after adrenalectomy in PA patients
From: Recovery from diabetes mellitus in primary aldosteronism patients after adrenalectomy
Factors | Univariate logistic regression | Multivariate logistic regression | ||
|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | |
Age (years) | 1.021 (0.969–1.077) | 0.434 | ||
Gender (female/male) | 1.000 (0.331–3.018) | 1.000 | ||
BMI (kg/m2) | 0.984 (0.825–1.174) | 0.857 | ||
Duration of hypertension (months) | 1.007 (1.000-1.015) | 0.057 | 1.020 (1.002–1.039) | 0.029 |
Duration of DM (months) | 1.005 (0.997–1.013) | 0.223 | ||
Order of hypertension and DM (hypertension-DM/DM-hypertension) | 0.416 (0.127–1.364) | 0.148 | ||
Hemoglobin (g/L) | 0.972 (0.935–1.011) | 0.155 | ||
Red blood cell (1012/L) | 0.363 (0.109–1.210) | 0.099 | 0.047 (0-38.342) | 0.371 |
Platelet (109/L) | 1.011 (1.000-1.022) | 0.046 | 1.058 (0.935–1.197) | 0.370 |
ALP (IU/L) | 0.975 (0.948–1.003) | 0.079 | 1.019 (0.847–1.226) | 0.840 |
Serum creatinine (µmol/L) | 1.016 (0.989–1.044) | 0.250 | ||
eGFR (mL/min/1.73 m2) | 0.971 (0.937–1.007) | 0.113 | ||
BUN (mmol/L) | 1.414 (0.817–1.593) | 0.438 | ||
Concentration of urinary K (mmol/L) | 1.025 (0.970–1.082) | 0.380 | ||
Concentration of urinary Na (mmol/L) | 0.982 (0.963–1.002) | 0.080 | 1.055 (0.920–1.209) | 0.445 |
Concentration of urinary Cl (mmol/L) | 0.984 (0.964–1.003) | 0.106 | ||
Concentration of urinary Ca (mmol/L) | 1.017 (0.681–1.521) | 0.933 | ||
Concentration of urinary Mg (mmol/L) | 1.245 (0.585–2.648) | 0.570 | ||
Concentration of urinary P (mmol/L) | 0.960 (0.826–1.116) | 0.594 | ||
24 h urinary K (mmol/24 h) | 1.026 (0.990–1.062) | 0.158 | ||
24 h urinary Na (mmol/24 h) | 0.997 (0.988–1.007) | 0.547 | ||
24 h urinary Cl (mmol/24 h) | 0.996 (0.986–1.006) | 0.416 | ||
24 h urinary Ca (mmol/24 h) | 1.233 (0.794–1.915) | 0.351 | ||
24 h urinary Mg (mmol/24 h) | 1.860 (0.857–4.034) | 0.116 | ||
24 h urinary P (mmol/24 h) | 1.199 (0.985–1.460) | 0.071 | 1.036 (0.622–1.725) | 0.892 |
ALD (lying position) (ng/dL) | 1.044 (0.984–1.108) | 0.150 | ||
ALD (standing position) (ng/dL) | 1.003 (0.951–1.058) | 0.910 | ||
ARR (lying position) | 1.001 (0.999–1.002) | 0.415 | ||
ARR (standing position) | 1.000 (0.999–1.002) | 0.380 | ||
PTC8 (Cortisol) (nmol/L) | 0.999 (0.995–1.002) | 0.446 | ||
PTC0 (Cortisol) (nmol/L) | 0.999 (0.989–1.008) | 0.769 | ||
ACTH (ng/L) | 1.012 (0.985–1.039) | 0.385 | ||
Total 24 h UFC (µg/24 h) | 1.007 (0.993–1.022) | 0.335 | ||
Fasting blood glucose before surgery (mmol/L) | 0.940 (0.776–1.138) | 0.524 | 1.338 (0.530–3.377) | 0.537 |
HbA1C before surgery (%) | 0.621 (0.350–1.101) | 0.103 | ||