NYHA I (n = 28) | NYHA II (n = 56) | NYHA III (n = 36) | F/Xc | P | P1 | P2 | P3 | |
---|---|---|---|---|---|---|---|---|
Age (Year) | 50.29 ± 5.08 | 52.73 ± 8.07 | 55.19 ± 5.40c | 4.223 | 0.017a | 0.119 | 0.005a | 0.089 |
BMI | 29.39 ± 3.75 | 29.91 ± 3.56 | 29.16 ± 2.99 | 0.577 | 0.563 | 0.513 | 0.786 | 0.305 |
HTN history (%) | 9 (32.1%) | 25 (44.6%) | 20 (55.6%) | 3.494 | 0.174 | 0.271 | 0.062 | 0.307 |
SBP (mmHg) | 121.96 ± 11.49 | 124.73 ± 11.38 | 128.61 ± 11.63 | 2.747 | 0.098 | 0.300 | 0.051 | 0.116 |
DBP (mmHg) | 82.14 ± 8.97 | 83.21 ± 7.89 | 85.42 ± 10.65 | 1.141 | 0.323 | 0.610 | 0.153 | 0.256 |
FBG (mg/dl) | 89.32 ± 12.78 | 91.82 ± 11.61 | 94.83 ± 10.03 | 1.865 | 0.160 | 0.348 | 0.059 | 0.221 |
FI (uIU/ml) | 9.90 ± 3.17 | 11.13 ± 4.21 | 12.24 ± 3.56 | 2.992 | 0.094 | 0.164 | 0.052 | 0.175 |
HOMA-IR | 2.22 ± 0.88 | 2.51 ± 0.98 | 2.86 ± 0.95c | 3.735 | 0.027a | 0.179 | 0.008a | 0.087 |
TC (mg/dl) | 199.14 ± 48.30 | 210.23 ± 44.43 | 213.64 ± 38.81 | 0.930 | 0.397 | 0.276 | 0.191 | 0.716 |
LDL (mg/dl) | 126.93 ± 40.11 | 129.56 ± 39.47 | 136.89 ± 34.26 | 0.628 | 0.536 | 0.766 | 0.302 | 0.370 |
HDL (mg/dl) | 46.18 ± 7.15 | 44.71 ± 8.02 | 43.39 ± 7.49 | 1.045 | 0.355 | 0.411 | 0.151 | 0.420 |
TGs (mg/dl) | 143.21 ± 34.38 | 148.73 ± 47.61 | 152.06 ± 29.47 | 0.388 | 0.679 | 0.552 | 0.382 | 0.698 |
Hemoglobin (g/dl) | 11.70 ± 1.10 | 11.66 ± 1.00 | 11.53 ± 0.83 | 0.316 | 0.730 | 0.874 | 0.477 | 0.505 |
BNP (Pg/ml) | 51.82 ± 9.54 | 58.34 ± 12.14b | 70.36 ± 13.86c,d | 19.870 | 0.001a | 0.022a | 0.001a | 0.001a |
Testosterone (ng/ml) | 3.79 ± 1.54 | 2.96 ± 0.75b | 2.49 ± 0.79c,d | 13.408 | 0.001a | 0.001a | 0.001a | 0.031a |
Testosterone deficiency (%) | 5 (17.9%) | 9 (16.1%) | 16 (44.4%)c,d | 18.798 | 0.002a | 0.001a | 0.836 | 0.002a |
LAEF (%) | 51.21 ± 9.63 | 48.71 ± 8.48 | 44.28 ± 6.06c,d | 6.169 | 0.003a | 0.187 | 0.001a | 0.012a |
ICAM-1 (ng/ml) | 372.25 ± 76.99 | 350.30 ± 75.91 | 429.75 ± 72.68c,d | 12.382 | 0.001a | 0.210 | 0.003a | 0.001a |
P- selectin (ng/ml) | 250.32 ± 94.32 | 315.55 ± 71.80b | 321.33 ± 95.45c | 6.840 | 0.002a | 0.001a | 0.001a | 0.750 |
NO (μM) | 14.94 ± 1.15 | 13.94 ± 0.79b | 13.75 ± 0.75c | 16.544 | 0.001a | 0.001a | 0.001a | 0.307 |
ACEIs/ARBs (%) | 10 (35.7%) | 22 (39.3%) | 12 (33.3%) | 0.349 | 0.840 | 0.751 | 0.842 | 0.564 |
CCB (%) | 5 (17.9%) | 12 (21.4%) | 7 (19.4%) | 0.159 | 0.924 | 0.701 | 0.872 | 0.819 |
BB (%) | 4 (14.3%) | 16 (28.6%) | 12 (33.3%) | 3.117 | 0.210 | 0.147 | 0.081 | 0.628 |
Diuretics (%) | 4 (14.3%) | 12 (21.4%) | 16 (44.4%)c,d | 8.779 | 0.012a | 0.432 | 0.010a | 0.019a |