Fig. 3

Methylation status of regulatory regions of SOCS1 (a) and SOCS3 (b) genes in the subcutaneous adipose tissues (SAT) of women with obesity (O) and ones with normal weight (NW). The methylated level of DNA is expressed as the estimated amount of methylated DNA to the unmethylated DNA levels ratio calculated for each sample using the fluorescence threshold cycle. The results were s expressed as fold change relative to the controls. Results were shown as median (interquartile ranges). The p-value was determined by Mann–Whitney U test