Table 4 Follow-up indicators for patients with Graves’ disease with normal liver function and liver dysfunction at different time points after treatment
From: Effect of liver dysfunction on outcome of radioactive iodine therapy for Graves’ disease
Indicator | 3 months | 6 months | 12 months | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Normal liver function (n = 277) | Liver dysfunction (n = 212) | Z/t | p value | Normal liver function (n = 249) | Liver dysfunction (n = 184) | Z/t | P | Normal liver function (n = 196) | Liver dysfunction (n = 163) | Z/t | p value | |
TSH (mIU/l) | 1.040 (0.005, 50.270) | 16.68 (0.01, 63.90) | − 2.457 | 0.014 | 1.580 (0.035, 17.330) | 6.315 (0.183, 26.455) | − 2.651 | 0.008 | 3.125 (0.262, 9.335) | 4.65 (1.230, 16.430) | − 2.242 | 0.025 |
FT3 (pmol/l) | 3.26 (1.70, 5.78) | 2.69 (1.44, 4.80) | 1.984 | 0.047 | 4.22 (3.38, 5.59) | 4.09 (3.23, 5.54) | 0.932 | 0.351 | 4.27 (3.73, 5.05) | 4.14 (3.56, 4.85) | 1.117 | 0.264 |
FT4 (pmol/l) | 9.12 (3.92, 19.37) | 6.86 (3.08, 15.09) | 1.863 | 0.062 | 16.36 (11.46, 21.91) | 16.97 (11.69, 21.61) | − 0.212 | 0.832 | 16.68 (12.41, 20.59) | 17.46 (14.12, 20.42) | − 0.796 | 0.426 |
TRAb (IU/ml) | 38.02 (24.99, 40.00) | 40.00 (16.51, 40.00) | − 0.247 | 0.805 | 22.93 (11.42, 40.00) | 36.30 (14.13, 40.00) | − 0.969 | 0.333 | 12.19 (3.78, 32.12) | 21.83 (11.65, 33.68) | − 1.700 | 0.089 |
TPOAb (IU/ml) | 600.0 (347.4, 600.0) | 548.6 (261.5, 600.0) | 1.902 | 0.057 | 562.7 (226.8, 600.0) | 510.7 (277.6, 600.0) | 0.119 | 0.905 | 336.8 (161.4, 596.8) | 319.7 (118.9, 511.2) | 1.146 | 0.252 |
TgAb (IU/l) | 414.2 (194.6, 607.6) | 402.9 (160.3, 658.5) | 0.363 | 0.716 | 400.0 (134.3, 691.2) | 310.2 (121.8, 541.3) | 1.185 | 0.236 | 153.3 (26.62, 524.4) | 145.75 (44.10, 463.78) | 0.021 | 0.983 |
Median heart rate (bpm) | 73.97 ± 11.73 | 70.81 ± 12.11 | 2.405 | 0.017 | 76.86 ± 16.29 | 72.00 ± 7.87 | 2.250 | 0.026 | 75.43 ± 10.22 | 75.05 ± 16.05 | 0.110 | 0.177 |