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Table 3 Overall follow-up indicators at different time points after RAI treatment

From: Effect of liver dysfunction on outcome of radioactive iodine therapy for Graves’ disease

Indicators

Baseline

3 months

6 months

12 months

xʹ2

Pʹ

Total

Total

x2

P

Total

x2

P

Total

x2

P

TSH (mIU/l)

0.005 (0.005, 0.010)

6.650 (0.008, 61.65)

 − 1.602

 < 0.001

3.800 (0.083, 22.323)

 − 0.079

0.425

4.000 (0.760, 13.620)

 − 0.022

0.824

404.89

 < 0.001

FT3 (pmol/l)

24.95 (14.60, 35.80)

2.96 (1.45, 5.43)

2.257

 < 0.001

4.14 (3.27, 5.42)

 − 0.543

 < 0.001

4.21 (3.66, 4.90)

 − 0.030

0.758

600.63

 < 0.001

FT4 (pmol/l)

60.29 (38.55, 100.00)

7.42 (3.07, 19.21)

2.178

 < 0.001

16.76 (11.58, 21.26)

0.546

 < 0.001

16.91 (13.61, 20.43)

 − 0.057

0.557

551.69

 < 0.001

TRAb (IU/ml)

14.32 (6.99, 32.35)

37.84 (16.53, 40.00)

 − 0.942

0.008

25.72 (11.75, 40.00)

 − 0.173

0.629

17.52 (5.38, 32.83)

 − 1.327

 < 0.001

25.055

 < 0.001

TPOAb (IU/ml)

295.5 (83.0, 563.8)

600.0 (321.8, 600.0)

 − 1.646

 < 0.001

537.6 (278.7, 600.0)

 − 0.061

0.831

333.6 (128.9, 557.5)

 − 1.110

 < 0.001

59.049

 < 0.001

TgAb (IU/l)

212.3 (39.39, 620.3)

405.1 (120.9, 660.0)

 − 0.939

0.001

318.4 (104.7, 650.5)

 − 0.415

0.146

149.6 (31.7, 499.5)

 − 0.622

0.029

17.692

0.001

Median heart rate (bpm)

93.23 ± 16.53

73.08 ± 12.64

1.438

 < 0.001

74.51 ± 13.70

 − 0.042

0.911

75.30 ± 12.44

 − 0.188

0.615

27.106

 < 0.001

  1. Data are expressed as median (lower quartile, upper quartile) unless otherwise indicated
  2. FT3 Free triiodothyronine, FT4 Free thyroxine, TgAb Antithyroglobulin antibody, TPOAb Thyroid peroxidase antibody, TRAb Thyrotropin receptor antibody, TSH Thyroid-stimulating hormone
  3. *Statistically significant (p < 0.05)