Skip to main content

Table 1 Baseline characteristics of the study subjects

From: Serum uric acid/creatinine ratio and free androgen index are synergistically associated with increased risk of polycystic ovary syndrome in obese women

Variables

Obese women with PCOS (n = 40)

Non-PCOS obese women (n = 40)

P

Age (years)

28.68 ± 5.65

26.98 ± 6.67

0.225

BMI (Kg/m 2 )

34.77 ± 4.95

33.85 ± 4.09

0.367

WC (cm)

102.06 ± 10.09

98.93 ± 7.68

0.122

Neck circumference (cm)

37.30 ± 1.99

36.88 ± 1.86

0.326

SBP (mm Hg)

125.18 ± 6.74

119.0 ± 3.62

< 0.001*

DBP (mm Hg)

81.70 ± 2.76

78.88 ± 3.49

< 0.001*

FPG (mmol/l)

4.67 ± 0.53

4.34 ± 0.53

0.006*

Fasting insulin (µU/ml)

4.77 (3.8–5.4)

4.38 (3.5–5.22)

< 0.001*

HOMA-IR

3.6 (0.7–26)

1.5 (0.6–4.10)

< 0.001*

TC (mmol/l)

4.13 (1.71–6.72)

3.67 (1.89–5.64)

0.098

TGs (mmol/l)

1.21 (0.66–3.39)

1.23 (0.76–2.60)

0.541

LDL-C (mmol/l)

2.10 (0.91–4.66)

2.165 (1.17–4.53)

0.941

HDL-C (mmol/l)

1.235 (0.36–2.5)

1.15 (0.39–2.51)

0.967

LH/FSH (IU/L)

3.77 (1.03–5.38)

1.11 (1.0-1.22)

< 0.001*

Estradiol (pmol/L)

235.69 (80.57–396.5)

201.31 (97–311)

0.064

DHEAS (µmol/L)

6.37 (2.18–9.98)

3.93 (1.9–7.78)

< 0.001*

SHBG (nmol/L)

33.05 (23.1–70.3)

78.15 (38.6–128)

< 0.001*

Total testosterone (nmol/L)

2.58 (0.77–4.2)

0.98 (0.09–2.42)

< 0.001*

FAI

8.75 (1.55–11.55)

1.21 (0.13–3.43)

< 0.001*

Uric acid (µmol/l)

343.86 ± 54.75

289.25 ± 44.39

< 0.001*

Creatinine (µmol/l)

79.32 ± 11.58

75.58 ± 14.01

0.197

UA/Cr ratio

4.38 ± 0.69

3.94 ± 0.88

< 0.001*

  1. Data are expressed as mean ± standard deviation, or median (minimum-maximum), PCOS Polycystic ovary syndrome, BMI Body mass index, WC Waist circumference, SBP Systolic blood pressure, DBP Diastolic blood pressure, FPG Fasting plasma glucose, HOMA-IR Homeostasis model assessment of insulin resistance, TC Total cholesterol, TGs Triglycerides, LDL-C Low density lipoprotein cholesterol HDL-C High density lipoprotein cholesterol, LH Luteinizing hormone, FSH Follicle stimulating hormone, DHEAS Dehydroepiandrosterone sulphate, SHBG Sex hormone binding globulin, FAI Free androgen index, UA/Cr Uric acid/creatinine.
  2. *P is significant if ≤ 0.05