From: Unique genetic variants of lean nonalcoholic fatty liver disease: a retrospective cohort study
Variables | Total | Non-NAFLD | NAFLD | P Value |
---|---|---|---|---|
N | 5338 | 2470 | 2868 | Â |
n (%) | ||||
 Metabolic syndromea | 1324(24.8) | 309(12.5) | 1015(35.4) |  < 0.001 |
 Hypertension | 2861(53.6) | 1131(45.8) | 1730(60.3) |  < 0.001 |
 Diabetes | 833(15.6) | 308(12.5) | 525(18.3) |  < 0.001 |
 Cardiopathy | 892(16.7) | 432(17.5) | 460(16.0) | 0.157 |
 Hyperlipidemia | 281(5.3) | 128(5.2) | 153(5.3) | 0.803 |
 Male | 2400(45.0) | 1170(47.4) | 1230(42.9) | 0.001 |
 Body mass index (kg/m2) |  |  |  |  < 0.001 |
 < 23 lean | 2012(37.7) | 1461(59.1) | 551(19.2) |  |
 23–24.9 overweight | 1354(25.4) | 535(21.7) | 819(28.6) |  |
 ≥ 25 obese | 1972(36.9) | 474(19.2) | 1498(52.2) |  |
Mean ± SD | ||||
 Age (years) | 69.19 ± 7.13 | 69.39 ± 7.36 | 69.02 ± 6.92 | 0.062 |
 Systolic blood pressure (mmHg) | 142.14 ± 22.19 | 139.22 ± 22.81 | 144.66 ± 21.33 |  < 0.001 |
 Diastolic blood pressure (mmHg) | 81.51 ± 11.78 | 80.58 ± 12.08 | 82.32 ± 11.45 |  < 0.001 |
 Waist circumference (cm) | 82.64 ± 9.26 | 78.36 ± 8.52 | 86.34 ± 8.22 |  < 0.001 |
 Waist-to-hip ratio | 0.88 ± 0.07 | 0.86 ± 0.07 | 0.9 ± 0.06 |  < 0.001 |
 ALT (U/L) | 24.65 ± 21.72 | 22.34 ± 21.75 | 26.64 ± 21.49 |  < 0.001 |
 AST (U/L) | 23.88 ± 12.59 | 23.54 ± 12.31 | 24.17 ± 12.83 | 0.068 |
 Ureophil (mmol/L) | 5.48 ± 1.53 | 5.44 ± 1.56 | 5.51 ± 1.5 | 0.107 |
 Fasting glucose (mmol/L) | 6.16 ± 1.72 | 5.91 ± 1.57 | 6.38 ± 1.8 |  < 0.001 |
 Hemoglobin (g/L) | 140.09 ± 14.15 | 138.61 ± 14.59 | 141.36 ± 13.63 |  < 0.001 |
 Platelet (109/L) | 197.14 ± 61.21 | 193.19 ± 67.7 | 200.55 ± 54.79 |  < 0.001 |
 Total cholesterol (mmol/L) | 5.08 ± 0.98 | 5.05 ± 1 | 5.11 ± 0.96 | 0.026 |
 Total bilirubin (µmol/L) | 15.78 ± 5.78 | 15.85 ± 5.77 | 15.72 ± 5.8 | 0.387 |
 Creatinine (µmol/L) | 69.8 ± 21.75 | 71.01 ± 25.5 | 68.77 ± 17.84 |  < 0.001 |
 HDL (mmol/L) | 1.25 ± 0.28 | 1.31 ± 0.29 | 1.19 ± 0.25 |  < 0.001 |
 LDL (mmol/L) | 3.17 ± 0.87 | 3.13 ± 0.88 | 3.21 ± 0.86 |  < 0.001 |
 TG (mmol/L) | 1.48 ± 1.09 | 1.21 ± 0.87 | 1.71 ± 1.2 |  < 0.001 |
 Uric Acid (µmol/L) | 344.36 ± 86.64 | 327.82 ± 82.36 | 358.61 ± 87.71 |  < 0.001 |