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Table 1 229 susceptibility differentially expressed genes (SDEGs) of T2DM in the skeletal muscle

From: Identification of the hub susceptibility genes and related common transcription factors in the skeletal muscle of Type 2 Diabetes Mellitus

Gene Symbol

ID

Gene Title

EVX1

207914_x_at

even-skipped homeobox 1

C17orf77

1553298_at

chromosome 17 open reading frame

MIR7-3HG

223973_at

MIR7-3 host gene

CDKN1A

202284_s_at

cyclin dependent kinase inhibitor 1A

TET2

1569385_s_at

tet methylcytosine dioxygenase 2

LOC101929926

237685_at

uncharacterized LOC101929926

SLC9A1

1554728_at

solute carrier family 9 member A1

NR4A1

202340_x_at

nuclear receptor subfamily 4 group A

WFDC1

219478_at

WAP four-disulfide core domain 1

NTM

241934_at

neurotrimin

ST18

1570307_s_at

ST18, C2H2C-type zinc finger

LINC00616

1561098_at

long intergenic non-protein coding R

WDR86-AS1

1560147_at

WDR86 antisense RNA 1

TMOD3

220800_s_at

tropomodulin 3

ZNF74

205881_at

zinc finger protein 74

SERPINA1

202833_s_at

serpin family A member 1

LOC100131662

236973_at

uncharacterized LOC100131662

ARSD

232423_at

arylsulfatase D

RAB15

221810_at

RAB15, member RAS oncogene family

ZNF660

1561361_at

zinc finger protein 660

GTF2A1

206521_s_at

general transcription factor IIA subunit

CARD16

1554744_at

caspase recruitment domain family me

CALCB

214636_at

calcitonin related polypeptide beta

FSTL4

1565910_at

follistatin like 4

DOK4

209690_s_at

docking protein 4

LINC00302

216935_at

long intergenic non-protein coding R

TMEM102

230633_at

transmembrane protein 102

VPS13B

1553852_at

vacuolar protein sorting 13 homolog

DICER1-AS1

1557063_at

DICER1 antisense RNA 1

STMN4

221236_s_at

stathmin 4

KCNH5

242502_at

potassium voltage-gated channel subf

TRIM14

203148_s_at

tripartite motif containing 14

PGLYRP1

207384_at

peptidoglycan recognition protein 1

NEK9

230153_at

NIMA related kinase 9

MTHFD2

234976_x_at

methylenetetrahydrofolate dehydroge

GPR78///CPZ

211062_s_at

G protein-coupled receptor 78///carb

RAB39B

238695_s_at

RAB39B, member RAS oncogene famil

TP63

211834_s_at

tumor protein p63

LYVE1

219059_s_at

lymphatic vessel endothelial hyalurona

RNF187

230662_at

ring finger protein 187

SNORA71A

1565858_at

small nucleolar RNA, H/ACA box 71A

MRPS31

243821_at

mitochondrial ribosomal protein S31

SPATA33

229660_at

spermatogenesis associated 33

LINC01395

1563070_at

long intergenic non-protein coding R

MTPN

223925_s_at

myotrophin

PCGEM1

234529_at

PCGEM1, prostate-specific transcript (

LOC101929796//

227067_x_at

notch homolog 2 N-terminal-like prot

FLJ32255

235291_s_at

uncharacterized LOC643977

TLR7

220146_at

toll like receptor 7

KCNQ1

211217_s_at

potassium voltage-gated channel subf

NFKBIE

203927_at

NFKB inhibitor epsilon

IKZF1

205038_at

IKAROS family zinc finger 1

THRA

214883_at

thyroid hormone receptor, alpha

RREB1

217411_s_at

ras responsive element binding protei

GALNT13

243779_at

polypeptide N-acetylgalactosaminyltr

ZNF391

1558658_at

zinc finger protein 391

GHSR

221360_s_at

growth hormone secretagogue recept

CD22

204581_at

CD22 molecule

PTGDR

215937_at

prostaglandin D2 receptor

ANLN

1552619_a_at

anillin actin binding protein

SLC25A14

211855_s_at

solute carrier family 25 member 14

SLC35F3

229065_at

solute carrier family 35 member F3

AOC1

203559_s_at

amine oxidase, copper containing 1

SERPINA10

220626_at

serpin family A member 10

PCBP1-AS1

1557727_at

PCBP1 antisense RNA 1

MROH9

221182_at

maestro heat like repeat family memb

DENND2D

221081_s_at

DENN domain containing 2D

CYP1B1-AS1

1553829_at

CYP1B1 antisense RNA 1

CLCA4

220026_at

chloride channel accessory 4

TAF1A-AS1

238491_at

TAF1A antisense RNA 1

CYR61

210764_s_at

cysteine rich angiogenic inducer 61

ADAMTS9

1554697_at

ADAM metallopeptidase with thromb

SYT16

239671_at

synaptotagmin 16

ZDHHC18

231900_at

zinc finger DHHC-type containing 18

HYAL3

211728_s_at

hyaluronoglucosaminidase 3

SKIDA1

1559266_s_at

SKI/DACH domain containing 1

SLC8B1

222727_s_at

solute carrier family 8 member B1

CCT8L2

220508_at

chaperonin containing TCP1 subunit 8

KLHL29

1554261_at

kelch like family member 29

PTK7

1555324_at

protein tyrosine kinase 7 (inactive)

LINC00887

1564485_at

long intergenic non-protein coding R

SPRY4-IT1

1566967_at

SPRY4 intronic transcript 1

FKBP15

231099_at

FK506 binding protein 15

PROSER2

230051_at

proline and serine rich 2

LOC100130987//

1562022_s_at

uncharacterized LOC100130987///RA

KCTD7///RABGEF

1555569_a_at

potassium channel tetramerization do

TSPYL6

231339_at

TSPY like 6

MYO5A

241966_at

myosin VA

BDNF

206382_s_at

brain derived neurotrophic factor

CALML6

1552402_at

calmodulin like 6

C3orf14

219288_at

chromosome 3 open reading frame 1

P4HA1

243335_at

prolyl 4-hydroxylase subunit alpha 1

PNPLA1

1553364_at

patatin like phospholipase domain co

CSTL1

234803_at

cystatin like 1

CTAG2

215733_x_at

cancer/testis antigen 2

GCG

206422_at

glucagon

LOC101928535

1561443_at

uncharacterized LOC101928535

UMODL1

1553183_at

uromodulin like 1

HGS

232627_at

hepatocyte growth factor-regulated ty

LOC105373460

234433_at

uncharacterized LOC105373460

KANK1

237162_at

KN motif and ankyrin repeat domains

BFSP2

207399_at

beaded filament structural protein 2

IGHM

211634_x_at

immunoglobulin heavy constant mu

TENM2

231867_at

teneurin transmembrane protein 2

DCAF5

1554558_at

DDB1 and CUL4 associated factor 5

SEMA6B

223567_at

semaphorin 6B

GPR84

223767_at

G protein-coupled receptor 84

FAM201A

1557014_a_at

family with sequence similarity 201 me

RORA

241760_x_at

RAR related orphan receptor A

LOC100509814

1562414_at

uncharacterized LOC100509814

MTBP

233436_at

MDM2 binding protein

FAM170B-AS1

1563254_a_at

FAM170B antisense RNA 1

KLRC2///KLRC1

206785_s_at

killer cell lectin like receptor C2///killer

DPP4

211478_s_at

dipeptidyl peptidase 4

ABCG5

220383_at

ATP binding cassette subfamily G me

DCDC2

222926_at

doublecortin domain containing 2

RBM47

222496_s_at

RNA binding motif protein 47

IGHV4-31///IGHA

234477_at

immunoglobulin heavy variable 4-31/

GNG8

233416_at

G protein subunit gamma 8

CD86

210895_s_at

CD86 molecule

LHFPL3-AS1

240366_at

LHFPL3 antisense RNA 1

ZBED3-AS1

1570204_at

ZBED3 antisense RNA 1

NIFK

234167_at

nucleolar protein interacting with the F

PDPN

208233_at

podoplanin

ARHGEF26-AS1

236575_at

ARHGEF26 antisense RNA 1

EFEMP1

228421_s_at

EGF containing fibulin like extracellular

IGKV1OR2-108

217378_x_at

immunoglobulin kappa variable 1/OR

CLEC12A

243106_at

C-type lectin domain family 12 memb

RUNX2

236859_at

runt related transcription factor 2

CDH12

207149_at

cadherin 12

FBXO36

1555195_at

F-box protein 36

FGF7

1555102_at

fibroblast growth factor 7

SAMSN1

220330_s_at

SAM domain, SH3 domain and nuclea

IQUB

1568924_a_at

IQ motif and ubiquitin domain contain

TTC34///LOC284

1565728_at

tetratricopeptide repeat domain 34///

CYP19A1

1554296_at

cytochrome P450 family 19 subfamily

PROZ

208034_s_at

protein Z, vitamin K dependent plasm

LOC101927809

1568633_a_at

uncharacterized LOC101927809

IL32

203828_s_at

interleukin 32

LOC284788

1557483_at

uncharacterized LOC284788

CRYBB2P1///CRY

206777_s_at

crystallin beta B2 pseudogene 1///crys

LOC374443

240572_s_at

C-type lectin domain family 2 membe

IL23A

220054_at

interleukin 23 subunit alpha

AKNAD1

1563834_a_at

AKNA domain containing 1

RASAL2

217194_at

RAS protein activator like 2

JUND

214326_x_at

JunD proto-oncogene, AP-1 transcript

LOC100996919//

207979_s_at

putative T-cell surface glycoprotein C

ANPEP

234458_at

alanyl aminopeptidase, membrane

TES

244870_at

testin LIM domain protein

LOC339807

1562776_at

uncharacterized LOC339807

RAB11FIP4

225746_at

RAB11 family interacting protein 4

FBF1

1556131_s_at

Fas binding factor 1

CAMK2A

207613_s_at

calcium/calmodulin dependent protei

SATB2-AS1

1553420_at

SATB2 antisense RNA 1

SCRG1

243984_at

stimulator of chondrogenesis 1

METTL6

1557991_at

methyltransferase like 6

HIPK1-AS1

1570080_at

HIPK1 antisense RNA 1

RFC1

208133_at

replication factor C subunit 1

IQCH

1569610_at

IQ motif containing H

CDR1

207276_at

cerebellar degeneration related protei

KCNH6

211046_at

potassium voltage-gated channel subf

RAB6B

210127_at

RAB6B, member RAS oncogene family

HTRA4

1553706_at

HtrA serine peptidase 4

MYH1

205951_at

myosin heavy chain 1

USP31

244441_at

ubiquitin specific peptidase 31

AGBL5

238889_at

ATP/GTP binding protein like 5

H2BFS

208579_x_at

H2B histone family member S

CRIP1

205081_at

cysteine rich protein 1

ANKRD22

238439_at

ankyrin repeat domain 22

LOC101928833

1562107_at

uncharacterized LOC101928833

PNLIPRP2

211766_s_at

pancreatic lipase related protein 2 (ge

MAMDC2-AS1

1559655_at

MAMDC2 antisense RNA 1

CD80

1555689_at

CD80 molecule

BAZ2A

215437_x_at

bromodomain adjacent to zinc finger

PYY

207080_s_at

peptide YY

SEMA3A

244849_at

semaphorin 3A

ADAMTS20

1553409_at

ADAM metallopeptidase with thromb

SFTA3

228979_at

surfactant associated 3

NSUN3

222886_at

NOP2/Sun RNA methyltransferase fam

NTN3

207640_x_at

netrin 3

ACTRT3

223665_at

actin related protein T3

PLEKHM3

1560069_at

pleckstrin homology domain containin

LOC100507165

236640_at

uncharacterized LOC100507165

GABRA2

1554308_s_at

gamma-aminobutyric acid type A rece

ZNF26

1555325_s_at

zinc finger protein 26

TPGS1

243600_at

tubulin polyglutamylase complex subu

PCNX4

201789_at

pecanex homolog 4 (Drosophila)

REG3G

231661_at

regenerating family member 3 gamma

LOC441454

239321_at

prothymosin, alpha pseudogene

SCGB1D2

206799_at

secretoglobin family 1D member 2

SMARCAD1

223197_s_at

SWI/SNF-related, matrix-associated ac

PPP1R1C

1555462_at

protein phosphatase 1 regulatory inhi

PCDHB13

232415_at

protocadherin beta 13

TBL1X

201867_s_at

transducin (beta)-like 1X-linked

CUL5

230393_at

cullin 5

LOC401098

1556609_at

uncharacterized LOC401098

STYX

235180_at

serine/threonine/tyrosine interacting p

KCNN2

220116_at

potassium calcium-activated channel

PWWP2A

228337_at

PWWP domain containing 2A

CCAR1

239014_at

cell division cycle and apoptosis regul

PLS1

205190_at

plastin 1

ZNF3

232497_at

zinc finger protein 3

SMIM10L2B///SM

227909_at

small integral membrane protein 10 lik

TRIM23

210994_x_at

tripartite motif containing 23

DKK3

202196_s_at

dickkopf WNT signaling pathway inhib

MFI2-AS1

242087_x_at

MFI2 antisense RNA 1

LZTFL1

222632_s_at

leucine zipper transcription factor like

WFDC6

1552396_at

WAP four-disulfide core domain 6

DGKE

1554623_x_at

diacylglycerol kinase epsilon

FGF9

239178_at

fibroblast growth factor 9

CCDC169

233298_at

coiled-coil domain containing 169

SOHLH1

1561403_at

spermatogenesis and oogenesis specif

RBMS3

242137_at

RNA binding motif single stranded int

ASPHD2

227015_at

aspartate beta-hydroxylase domain co

ZNF329

219765_at

zinc finger protein 329

LINC00674

225054_x_at

long intergenic non-protein coding R

IDS

236823_at

iduronate 2-sulfatase

LOC286177

1562365_at

uncharacterized LOC286177

HYAL4

220249_at

hyaluronoglucosaminidase 4

HOXA13

231786_at

homeobox A13

LAMA2

216839_at

laminin subunit alpha 2

C4orf33

1552372_at

chromosome 4 open reading frame 3

FLJ35934

1564383_s_at

FLJ35934

HSPD1

241716_at

heat shock protein family D (Hsp60) m

NLGN4X

221933_at

neuroligin 4, X-linked

LOC101930081

233153_at

uncharacterized LOC101930081

CLEC2D

220132_s_at

C-type lectin domain family 2 membe

TRA2B

239447_at

transformer 2 beta homolog (Drosoph

NBAS

240579_at

neuroblastoma amplified sequence