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Table 4 Univariate and multivariate analysis of gallbladder cancer risk in the patients without GSD

From: Elevated serum triglyceride levels may be a key independent predicting factor for gallbladder cancer risk in gallbladder stone disease patients: a case–control study

 

Univariate

Multivariate

 

β

OR

95%CI

P value

β

OR

95%CI

P value

Gender(F)

0.627

1.872

1.624 ~ 2.157

 < 0.001

0.671

1.956

1.502 ~ 2.546

 < 0.001

BMI

0.031

1.032

1.010 ~ 1.055

0.004

0.014

1.014

0.993 ~ 1.035

0.184

TG

1.739

5.690

4.985 ~ 6.494

 < 0.001

1.284

3.611

3.056 ~ 4.267

 < 0.001

TC

0.030

1.030

0.962 ~ 1.104

0.398

-

-

-

-

HDL-c

-0.433

0.649

0.605 ~ 0.696

 < 0.001

-0.534

0.586

0.516 ~ 0.666

 < 0.001

LDL-c

1.124

3.078

2.810 ~ 3.372

 < 0.001

0.889

2.432

2.147 ~ 2.756

 < 0.001

HOMA-IR

1.695

5.447

4.791 ~ 6.192

 < 0.001

2.168

8.739

7.092 ~ 10.769

 < 0.001

DM

0.238

1.269

1.019 ~ 1.579

0.033

-4.133

0.016

0.008 ~ 0.033

 < 0.001

NAFLD

0.565

1.760

1.515 ~ 2.045

 < 0.001

-0.305

0.737

0.506 ~ 1.074

0.113

DBP

-0.004

0.996

0.990 ~ 1.003

0.309

-

-

-

-

SBP

-0.011

0.989

0.985 ~ 0.993

 < 0.001

/

/

/

/

FINS

0.571

1.771

1.701 ~ 1.843

 < 0.001

*

*

*

*

FBG

-0.135

0.874

0.830 ~ 0.920

 < 0.001

*

*

*

*

HBP

-0.491

0.612

0.518 ~ 0.723

 < 0.001

-0.430

0.650

0.456 ~ 0.928

0.018

HTG

2.991

19.906

16.492 ~ 24.027

 < 0.001

/

/

/

/

  1. BMI Body mass index, TG Triglyceride, TC Total cholesterol, HDL-c High density lipoprotein cholesterol, LDL-c Low density lipoprotein cholesterol, NAFLD Nonalcoholic fatty liver disease, SBP Systolic blood pressure, DBP Diastolic blood pressure, FBG Fasting blood glucose, FINS Fasting blood insulin, HOMA-IR Homeostasis Model Assessment of insulin resistance, HTG Hypertriglyceridemia, HBP High blood pressure, DM Diabetes mellitus
  2. eliminated for the definition of HOMA-IR in multivariate regression
  3. — eliminated for no statistical significance in univariate regression
  4. / eliminated for the collinear/redundant correlation between SBP and HBP; TG and HTG in multivariate regression