Table 1 Baseline characteristics in the MEDIM intervention study
Variables | Intervention n = 48 | Control n = 44 | P-value |
|---|---|---|---|
Age (years) | 47.9 (10.4) | 48.9 (9.05) | 0.63 |
Male sex, n (%) | 23 (46) | 22 (47.8) | 1.00 |
Proneurotensin, pmol/L, median (IQR+++) | 119.3 (92.8–156.0) | 104.5 (90.4–156.6) | 0.69 |
Body weight (kg) | 85.5 (15.2) | 80.0 (13.1) | 0.06 |
Body mass index(kg/m2) | 31.0 (4.4) | 29.6 (3.6) | 0.09 |
Waist circumference men(cm) | 108.2 (9.6) | 106.1 (8.9) | 0.45 |
Waist circumference women(cm) | 100.7 (8.1) | 97.2 (8.1) | 0.13 |
Insulin Sensitivity Index, median (IQR+++) | 62.4 (46.0, 99.5) | 73.3 (56.7, 118.0) | 0.16 |
Systolic blood pressure (mmHg) | 121.6 (13.3) | 126.9 (16.1) | 0.08 |
Diastolic blood pressure (mm Hg) | 77.6 (8.4) | 79.7 (11.2) | 0.30 |
Fasting glucose (mmol/L) | 5.6 (0.5) | 5.4 (0.7) | 0.25 |
2-h glucose (mmol/L) | 6.6 (1.8) | 6.5 (1.8) | 0.87 |
HbA1C (mmol/mol) HbA1C in % | 34 (4.7) 5.3% (0.4) | 35(4.4) 5.4% (0.4) | 0.33 |
Lipid-lowering drugs, n (%) | 1 (2) | 0 (0) | 1.00∞ |
LDL-cholesterol (mmol/L) | 3.4 (0.7) | 3.3 (0.9) | 0.51 |
HDL-cholesterol (mmol/L) | 1.3 (0.3) | 1.3 (0.4) | 0.97 |
First-degree Family history T2D, n (%) | 34 (68) | 24 (52.2) | 0.14 |
Education < HS+, n (%) | 7 (14) | 16 (34.8) | 0.03 |
Unemployment, n (%) | 26 (52) | 24 (52.2) | 1.00 |
Smoking, n (%) | 8 (16) | 8 (17.4) | 0.86 |
Physical activity (MET++-hours/week), median (IQR+++) | 8.5 (0-47.6) | 12.4 (0-66.3) | 0.32* |
Moderately active**, n (%) | 18 (36) | 26 (56.5) | 0.05 |
Total fat intake (g/d) | 86.1 (29.3) | 98.3 (34.6) | 0.08 |
Total carbohydrate intake (g/d) | 198.92 (63.4) | 187.53 (71.2) | 0.06 |
Total protein intake (g/d) | 85.92 (30.8) | 74.66 (19.8) | 0.05 |
Mean caloric intake (kcal) | 1886.3 (619) | 2052.3 (616) | 0.21 |