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Table 3 Multivariate logistic regression analysis of factors associated with the incidence of CAC

From: Relationship between a novel non–insulin-based metabolic score for insulin resistance (METS‐IR) and coronary artery calcification

 

Model 1

Model 2

Model 3

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

METS-IR

1.064 (1.040, 1.089)

< 0.001

1.041 (1.017, 1.066)

0.001

1.046 (1.019, 1.073)

0.001

METS-IRa

1.717 (1.304, 2.262)

< 0.001

1.406 (1.057, 1.871)

0.019

1.499 (1.091, 2.060)

0.013

TyG

1.813 (1.442, 2.278)

< 0.001

1.415 (1.110, 1.804)

0.005

1.439 (1.103, 1.878)

0.007

TyGb

2.079 (1.594, 2.710)

< 0.001

1.591 (1.198, 2.113)

0.001

1.730 (1.264, 2.368)

0.001

TG/HDL-C

1.105 (1.038, 1.176)

0.002

1.071 (1.004, 1.143)

0.037

1.076 (1.003, 1.155)

0.040

TG/HDL-Cc

1.892 (1.443, 2.480)

< 0.001

1.685 (1.275, 2.228)

< 0.001

1.770 (1.301, 2.410)

< 0.001

  1. a The OR was examined regarding lower METS-IR as reference, b The OR was examined regarding lower TyG as reference, c The OR was examined regarding lower TG/HDL-C as reference.
  2. Model 1: adjusted for age, sex
  3. Model 2: adjusted for variables included in Model 1 and smoking, diabetes, hypertension
  4. Model 3: adjusted for variables included in Model 2 and systolic blood pressure, diastolic blood pressure, total cholesterol, low-density lipoprotein cholesterol, creatinine, high sensitivity C-reactive protein, hemoglobin Alc. CAC coronary artery calcification, METS-IR metabolic score for insulin resistance, TyG triglyceride-glucose index, TG triglyceride, HDL-C high-density lipoprotein cholesterol, OR odd ratio, CI confidence interval