Association between triglyceride–glucose index and nonalcoholic fatty liver disease in type 2 diabetes mellitus

BMC Endocrine Disorders

Table 4 Subgroup analysis of the association between TyG index and NAFLD

	Stratified Group	OR (95% CI)	P value	P for interaction
Age, years	<65	2.35 (1.83‒3.02)	<0.001	0.043
Age, years	≥ 65	1.49 (0.65‒3.39)	0.343	0.043
Sex	Female	2.69 (1.67‒4.32)	<0.001	0.486
Sex	Male	2.09 (1.59‒2.76)	<0.001	0.486
BMI, kg/m²	<25	2.80 (2.01‒3.91)	<0.001	<0.001
BMI, kg/m²	≥ 25	1.86 (1.33‒2.60)	<0.001	<0.001
HDL-C, mmol/L	<1	2.76 (1.98‒3.83)	<0.001	<0.001
HDL-C, mmol/L	≥ 1	2.26 (1.65‒3.11)	<0.001	<0.001
AST/ALT ratio	<0.9	1.63 (1.13‒2.34)	0.009	0.011
AST/ALT ratio	≥ 0.9	2.63 (1.91‒3.62)	<0.001	0.011

BMI: body mass index; ALT: alanine transferase; AST: aspartate transferase; HDL-C: high-density lipoprotein cholesterol; TyG: triglycerides and glucose index
Adjusted for age, sex, BMI, hypertension, smoking status, drinking habits, duration of diabetes mellitus, AST and ALT levels, HbA1C, FBG, UA, TC, and HDL-C levels

ISSN: 1472-6823