The interaction between rs 3,807,992 genotypes with the dietary inflammatory index on Leptin, Leptin resistance, and Galectin 3 in obese and overweight women

Table 3 The association between EDII across and rs 3,807,992 genotypes on the leptin, and Galectin3 in obese and overweight (n = 363)

Variables	Models	EDII score		P-value^{^*}	rs 3,807,992 genotypes		P-value^{^*}
Variables	Models	β	95% CI	P-value^{^*}	β	95% CI	P-value^{^*}
Leptin (mg/l)	Crude	2.34	−22.52,27.21	0.85^{^}	1.32	−3.73,6.38	0.60
	Model1	14.03	−8.57,36.65	0.22^*	−0.71	−5.4,3.91	0.76
	Model2	16.73	1.56,39.32	0.04^*	2.53	−3.42,8.48	0.39
Leptin resistance	Crude	0.57	−0.36,1.51	0.22^{^}	0.02	−1.24,0.17	0.72
	Model1	0.49	−0.24,1.23	0.18^*	−0.01	−0.16,0.13	0.85
	Model2	0.55	0.00,1.30	0.06^*	0.08	0.00,0.28	0.08
Galectin3 (mg/l)	Crude	21.45	−19.47,62.37	0.30^{^}	−0.80	−3.93,2.31	0.60
	Model1	0.82	−0.59,2.25	0.25^*	0.06	−3.84,3.97	0.97
	Model2	0.91	−0.64,2.48	0.24^*	1.08	−3.40,5.58	0.62

EDII energy-adjusted dietary inflammatory index
Model 1: additionally adjusted for age, BMI, total energy intake, and physical activity
Model 2: additionally adjusted for, economic status, education level, age of starting obesity, losing weight history
^{^}Significant level in the crude model
^*Significant level after adjustment by Model1, 2
P < 0.05 consider as significant, P = 0.06, and 0.07 consider as marginally significant

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