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Table 1 Weighted characteristics of the NAFLD and non-NAFLD groups

From: Association of glycated hemoglobin with non-alcoholic fatty liver disease patients and the severity of liver steatosis and fibrosis measured by transient elastography in adults without diabetes

 

Non-NAFLD

(n = 1679)

NAFLD

(n = 1319)

P value

Age(years)

44.1 ± 18.1

49.8 ± 16.2

< 0.0001

Age (%)

  

< 0.0001

  18-39y

47.20

30.50

 

  40-59y

28.70

40.20

 

  60-80y

24.10

29.20

 

Sex (%)

  

< 0.0001

  Male

45.00

53.20

 

  Female

55.00

46.80

 

Race (%)

  

< 0.0001

  Non-Hispanic White

62.80

63.80

 

  Non-Hispanic Black

12.90

9.20

 

  Hispanic

5.60

10.50

 

Other Race

18.70

16.50

 

Smoking behavior (%)

  

0.0116

  Current smoke

14.70

11.80

 

  Ever smoke

21.80

25.40

 

  Never smoke

63.50

62.80

 

Hypertension (%)

  

< 0.0001

  No

73.80

52.20

 

  Yes

26.20

47.80

 

activity level

  

< 0.0001

  inactive

30.90

39.70

 

  Moderate

10.90

8.90

 

  active

58.20

51.40

 

BMI (Kg/m2)

26.1 ± 5.4

32.6 ± 6.9

< 0.0001

BMI (%)

  

< 0.0001

  BMI < 25

45.70

7.80

 

  25 ≤ BMI < 30

35.30

31.80

 

  BMI ≥ 30

19.00

60.40

 

WC (cm)

91.1 ± 13.5

107.6 ± 14.5

< 0.0001

ALT (IU/L)

19.4 ± 14.4

25.8 ± 16.6

< 0.0001

AST (IU/L)

21.0 ± 10.8

22.4 ± 11.2

0.0003

ALP(IU/L)

74.1 ± 24.2

79.0 ± 21.9

< 0.0001

GGT (IU/L)

21.8 ± 21.5

33.3 ± 38.9

< 0.0001

Serum creatinine (mg/dL)

0.9 ± 0.2

0.9 ± 0.4

0.1881

Fasting glucose(mg/dL)

90.1 ± 8.2

94.6 ± 9.3

< 0.0001

HbA1c (%)

  

< 0.0001

  Q1(4.1–5.1%)

27.6

16.1

 

  Q2(5.2–5.4%)

34.2

28.5

 

  Q3(5.5–5.6%)

19.7

20.9

 

  Q4(5.7–6.4%)

18.5

34.5

 

Total cholesterol (mg/dL)

186.0 ± 38.2

195.4 ± 38.2

< 0.0001

Triglyceride (mg/dL)

109.8 ± 61.3

161.8 ± 118.1

< 0.0001

HDL-cholesterol (mg/ dL)

57.1 ± 14.1

50.1 ± 13.5

< 0.0001

CAP (dB/m)

214.2 ± 33.7

310.0 ± 35.6

< 0.0001

LSM (kPa)

4.9 ± 3.3

6.1 ± 5.2

< 0.0001

  1. Mean ± SD was for continuous variables. The p-Value was calculated by weighted linear regression model. % was for categorical variables. The p-Value was calculated by the weighted chi-square test
  2. Abbreviations: NAFLD Non-alcoholic fatty liver disease, BMI Body mass index, WC Waist circumference, ALT Alanine aminotransferase, AST Aspartate aminotransferase, ALP Alkaline phosphatase, GGT Gamma-glutamyl transpeptidase, HbA1c Glycosylated hemoglobin A1c, HDL High-density lipoprotein, LSM Liver stiffness measurement, CAP Controlled attenuation parameter