Are there any interactions between modified Nordic-style diet score and MC4R polymorphism on cardiovascular risk factors among overweight and obese women? A cross-sectional study

Table 1 Characteristics of the study participants among MND tertiles

Variable	T1 (n = 73)	T2 (n = 160)	T3 (n = 169)	P-value	P-value*
Demographic variables
Age (years)	36.42 ± 9.51	35.85 ± 9.10	37.54 ± 8.89	0.23	0.23^b
PA (MET-minutes/week)	989.46 ± 1925.63	1031.06 ± 1994.74	1409.05 ± 2200.22	0.32	0.29^b
Anthropometric parameters
Weight (kg)	78.40 ± 11.17	81.52 ± 12.86	82.32 ± 12.41	0.07	0.06^a
Height (m)	160.10 ± 5.70	161.56 ± 5.87	161.38 ± 5.90	0.18	0.15^a
BMI (kg/m²)	30.81 ± 4.58	31.16 ± 4.40	31.54 ± 4.06	0.45	0.58^b
WC (cm)	98.20 ± 9.59	99.62 ± 10.56	100.19 ± 9.80	0.37	0.74^a
WHR	0.93 ± 0.04	1.50 ± 7.19	0.93 ± 0.05	0.47	0.77^a
Body composition
BFM (kg)	33.71 ± 8.45	34.96 ± 9.27	34.96 ± 8.38	0.55	0.72^a
FFM (kg)	45.20 ± 4.75	46.36 ± 5.79	47.25 ± 5.93	0.03	0.44^a
VFL	18.31 ± 22.92	15.96 ± 3.35	16.79 ± 10.76	0.39	0.04^a
Blood pressure
SBP (mmHg)	109.46 ± 12.46	109.95 ± 15.58	113.28 ± 14.86	0.13	0.30
DBP (mmHg)	78.86 ± 10.32	77.25 ± 10.29	77.42 ± 10.56	0.64	0.77
Blood parameters
FBS (mmol/dl)	87.45 ± 11.26	87.36 ± 9.84	87.60 ± 8.99	0.98	0.81
HOMA-IR	3.33 ± 1.18	3.41 ± 1.36	3.31 ± 1.23	0.85	0.89
Total Cholesterol (mg/dl)	190.62 ± 36.95	180.88 ± 35.46	186.91 ± 35.53	0.28	0.52
TG (g/dl)	106.50 ± 47.84	121.10 ± 65.88	127.94 ± 76.91	0.23	0.29
HDL (mg/dl)	46.57 ± 10.05	46.32 ± 9.83	46.78 ± 11.88	0.95	0.64
LDL (mg/dl)	91.45 ± 22.22	95.33 ± 24.25	96.52 ± 24.67	0.51	0.54
LDL/HDL	2.01 ± 0.50	2.12 ± 0.61	2.14 ± 0.59	0.46	0.48
CHOL/HDL	4.46 ± 2.57	4.03 ± 1.04	4.21 ± 1.31	0.32	0.39
Inflammatory marker
hs-CRP (mg/ L)	5.50 ± 5.39	3.78 ± 4.75	4.19 ± 4.13	0.14	0.21

Variables are presented as mean ± SD for continuous
P values from t test for continuous variables
Significant items with a P value < 0.05 are bolded
PA physical activity, BMI Body mass index, WC waist circumference, WHR waist height ratio, BFM body fat mas, FFM fat free mass, VFL visceral fat level, SBP Systolic blood pressure, DBP Diastolic Blood Pressure, FBS Fasting blood sugar, HOMA-IR Homeostatic Model Assessment for Insulin Resistance, TG Triglyceride, LDL Low density lipoprotein, HDL, High density lipoprotein, hs-CRP High sensitivity C-reactive protein
^*P-value was found by ANCOVA, and adjusted for age, BMI, physical activity, and total energy intake
^aBMI considered as collinear, and adjusted for age, physical activity, and total energy intake
^bRemoved the collinear variable from the GLM as confounders

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