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Table 1 Baseline characteristics of study population according to HOMA-IR level

From: Metabolic signatures of insulin resistance in non-diabetic individuals

Variable

HOMA-IR level

P-value

< 1.95

(n = 223)

≥ 1.95

(n = 180)

Gender, N (%)

Female

93 (41.7)

104 (57.8)

0.001

Male

130 (58.3)

76 (42.2)

Age (year)

56.80 ± 13.28

51.94 ± 9.94

 < 0.001

BMI (kg/m2)

25.05 ± 4.56

26.17 ± 4.43

 < 0.001

WC (cm)

88.57 ± 11.84

98.60 ± 10.89

 < 0.001

HC (cm)

97.6 ± 10.4

105.8 ± 8.9

 < 0.001

SBP (mmHg)

129.3 ± 21.19

128.8 ± 18.56

0.81

DBP (mmHg)

79.26 ± 11.82

80.77 ± 11.14

0.195

Education years, N (%)

  

0.015

  < 1 year

47 (33.2)

38 (21.1)

  1–7 years

76 (34.1)

58 (32.2)

  8–12 years

48 (21.5)

57 (31.7)

  > 12 years

25 (11.2)

27 (15.0)

FPG (mg/dL)

85.5 ± 9.3

90.2 ± 6.9

 < 0.001

HbA1c (%)

5.41 ± 0.387

5.57 ± 0.337

 < 0.001

Fructosamine (µmol/L)

233 ± 19

234 ± 25

0.81

TG (mg/dL)

104.1 ± 52.42

157.3 ± 88.86

 < 0.001

Chol (mg/dL)

162.2 ± 33.54

174.1 ± 34.60

0.001

HDL-C (mg/dL)

44.56 ± 11.36

39.14 ± 11.13

 < 0.001

Non-HDL Chol (mg/dL)

117.7 ± 33.77

134.9 ± 34.25

 < 0.001

ALT (IU/L)

17.79 ± 9.32

23.46 ± 13.02

 < 0.001

AST (IU/L)

22.74 ± 9.12

23.41 ± 7.84

0.43

Uric acid (mg/dL)

4.82 ± 1.20

5.42 ± 1.40

 < 0.001

  1. Continuous variables are presented as mean ± SD and categorical variables as Number (%)
  2. BMI Body mass index, WC Waist circumference, HC Hip circumference, SBP Systolic blood pressure, DBP Diastolic blood pressure, FPG Fasting plasma glucose, TG Triglycerides, Chol Cholesterol, HDL-C High-density cholesterol, ALT Alanine aminotransferase