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Table 1 Clinical characteristics of patients of Norwegian and Pakistani ethnicity

From: Fetuin-A mediates the difference in adipose tissue insulin resistance between young adult pakistani and norwegian patients with type 2 diabetes

 

Norwegian (n = 21)

Pakistani (n = 18)

Age (years)

42 (6)

41 (8)

BMI (kg/m2)

37.2 (6.0)

30.9 (9.4)**

Fasting C-peptide (pmol/L)

1162 ± 458

977 ± 373

Fasting insulin (pmol/L)

166 (160)

209 (193)

Fasting plasma glucose (mmol/L)

10.7 ± 3.2

10.6 ± 3.3

HbA1c (% mmol/mol)

7.3/56 (1.4/13)

8.7/72 (2.9/31)*

HDL cholesterol (mmol/L)

1.03 ± 0.21

1.08 ± 0.24

LDL cholesterol (mmol/L)

2.7 ± 0.8

2.6 ± 0.6

Lean body mass (kg)

67.1 ± 12.6

54.2 ± 12.2**

Men (%)

10 (48%)

9 (50%)

Total body fat (%)

36.9 ± 9.6

34.2 ± 7.7

Total body fat mass (kg)

39.5 ± 12.0

28.0 ± 8.2**

Thigh area (AU)

337 ± 57.7

294 ± 65.8*

Thigh SAT

165 ± 64.3

137 ± 59.5

Thigh SAT/area

0.47 ± 0.12

0.45 ± 0.13

Total cholesterol (mmol/L)

4.5 ± 1.0

4.7 ± 1.3

Triglycerides (mmol/L)

1.6 (1.1)

1.4 (1.1)

Waist circumference (cm)

114.3 ± 10.9

106.5 ± 17.4*

Hip circumference (cm)

114.8 ± 9.6

104.9 ± 8.8**

Waist-hip ratio

1.00 ± 0.09

1.01 ± 0.09

Weight (kg)

106.8 ± 13.6

90.1 ± 23.4**

Years with diabetes

5 (9)

9 (7)*

Diabetes treatment n(%)

  

  OAD / NPH insulin ± OAD

11 (52%) / 10 (48%)

5 (28%) / 13 (72%)

Other medications

  

  Statins

10 (48%)

4 (22%)

  Blood pressure lowering agents

8 (38%)

7 (39%)

Self-reported complications

  

  Macrovascular

2 (10%)

3 (17%)

  Retinopathy

2 (10%)

3 (17%)

  Nephropathy or microalbuminuria

2 (10%)

6 (33%)

  Neuropathy

1 (5%)

3 (17%)

  Diabetic foot ulcers

1 (5%)

0 (0%)

  Others (ED, fatty liver, periodontitis)

5 (24%)

6 (33%)

Co-morbidities

  

  Astma/COPD

4 (19%)

4 (22%)

  Psychiatric conditions

4 (19%)

1 (6%)

  GI disease

5 (24%)

2 (11%)

  Other endocrine disorders

2 (10%)

3 (17%)

  Smoking

10

1

Parity in women

  

  0–2

11

4

  3–5

0

5

  1. For normally distributed parameters, means ± SD are given, and for comparisons we used Student’s t-test. For non-normally-distributed parameters, medians (interquartile ranges) are given, and for comparisons we used the Mann–Whitney U test. Median HbA1c-values are reported as NGSP-%/IFCC-mmol/mol with interquartile range in parentheses. *p < 0.05 and **p < 0.01. Parity was defined as the number of live-born children each woman had given birth to. OAD oral antidiabetic drugs metformin and/or sulfonylureas. ED erectile dysfunction, COPD chronic obstructive pulmonary disease, GI gastro-intestinal, AU arbitrary units, SAT subcutaneous adipose tissue