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Table 1 Demographic and clinical characteristics of patients with Graves’ disease and PTC

From: Graves’ disease and papillary thyroid carcinoma: case report and literature review of a single academic center

Demographic/clinical data

n = 50

%

Age

  < 55

38

76%

  >  = 55

12

24%

Sex

 Female

41

82%

 Male

9

18%

TSI

 Positive

23

46%

 Negative

2

4%

 Unknown

25

50%

Initial stage

 Stage 1

39

78%

 Stage 2

11

22%

 Stage 3

0

0%

 Stage 4

0

0%

Evolution

 Recurrence

1

2%

 No recurrence

21

42%

 Unknown

28

56%

Diagnosis

 Incidental

24

48%

 Suggested

26

52%

Treatment used

 Thyroidectomy

38

76%

 Lobectomy

6

12%

 Thyroidectomy + RAI

6

12%

Hyperthyroidism difficult to treat?a

 Yes

5

10%

 No

45

90%

Focality

 Unifocal

33

66%

 Multifocal

17

34%

BRAF

 Yes

7

14%

 No

4

8%

 Unknown

39

78%

Size

 Carcinoma (< = 1 cm)

36

72%

 Carcinoma (> 1 cm)

14

28%

  1. aHyperthyroidism difficult to treat was defined as a Yes if documented by primary Endocrinologist that patient was not responding to average thionamide doses and needing to refer patient for definitive therapy due to absent response
  2. TSI Thyroid stimulating antibody, RAI Radioactive iodine, PTC Papillary thyroid cancer