Table 3 Summary of TIGIT expression in 34 anaplastic thyroid carcinomas (ATCs)
case no | predominat tumor cell morpology | TMN stage | positive tumor cell morphology | immune cell | IHC score | ||
|---|---|---|---|---|---|---|---|
type of infiltrate | density | predominat cell | |||||
1 | pleomorphic/giant | T4bN1bM1 | pleomorphic/gaint | diffuse | high | macrophage | 2 + |
2 | pleomorphic/giant | T4bN0MO | pleomorphic/gaint | diffuse | high | lymphocyte | 2 + |
3 | composite (FTC) | T4bN1bM0 | pleomorphic/gaint | diffuse | high | lymphocyte | 2 + |
4 | pleomorphic/giant | T4aN0M0 | pleomorphic/gaint | diffuse | high | neutrophil | 2 + |
5 | pleomorphic/giant | T4bN0MO | pleomorphic/gaint | diffuse | high | lymphocyte | 1 + |
6 | epithelioid/squamoid | T4bN1aM1 | pleomorphic/gaint | diffuse | high | lymphocyte | 1 + |
7 | spindle | T4bN1bM0 | pleomorphic/gaint | diffuse | low | lymphocyte | 1 + |
8 | composite (PTC) | T4bN1M1 | pleomorphic/gaint | diffuse | low | lymphocyte | 1 + |
9 | pleomorphic/giant | T4aN1bM0 | pleomorphic/gaint | diffuse | low | lymphocyte | 1 + |
10 | pleomorphic/giant | T4aNXMX | pleomorphic/gaint | diffuse | high | neutrophil | 1 + |
11 | epithelioid/squamoid | T4aN1M0 | pleomorphic/gaint | diffuse | high | lymphocyte | 1 + |
12 | spindle | T4aN1M0 | pleomorphic/gaint | diffuse | high | lymphocyte | 1 + |
13 | spindle | T4aN1bM0 | pleomorphic/gaint | diffuse | high | lymphocyte | 1 + |
14 | spindle | T4aNXMX | pleomorphic/gaint | diffuse | high | lymphocyte | 1 + |
15 | composite (FTC) | T3bNXM0 | pleomorphic/gaint | diffuse | high | macrophage | 1 + |
16 | pleomorphic/giant | TXNXM0 | pleomorphic/gaint | focal | low | lymphocyte | 1 + |
17 | spindle | N/A | pleomorphic/gaint | diffuse | low | lymphocyte | 1 + |
18 | pleomorphic/giant | T4bN1bM1 | diffuse | low | neutrophil | 0 | |
19 | epithelioid/squamoid | T4bN1M1 | diffuse | high | lymphocyte | 0 | |
20 | pleomorphic/giant | T4aN1aM0 | diffuse | low | macrophage | 0 | |
21 | spindle | T4aN1bM1 | scattered | low | lymphocyte | 0 | |
22 | epithelioid/squamoid | T2N1aM1 | diffuse | high | lymphocyte | 0 | |
23 | spindle | T1aNXM1 | diffuse | high | lymphocyte | 0 | |
24 | composite (PTC) | TXN1bM0 | diffuse | low | lymphocyte | 0 | |
25 | composite (PTC) | TXNXM1 | diffuse | high | macrophage | 0 | |
26 | composite (FTC) | N/A | diffuse | high | lymphocyte | 0 | |
27 | epithelioid/squamoid | N/A | diffuse | low | lymphocyte | 0 | |
28 | epithelioid/squamoid | N/A | focal | low | lymphocyte | 0 | |
29 | epithelioid/squamoid | N/A | diffuse | low | lymphocyte | 0 | |
30 | epithelioid/squamoid | N/A | diffuse | high | lymphocyte | 0 | |
31 | others (rhabdoid) | N/A | diffuse | low | macrophage | 0 | |