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Fig. 4 | BMC Endocrine Disorders

Fig. 4

From: Role of human organic cation transporter-1 (OCT-1/SLC22A1) in modulating the response to metformin in patients with type 2 diabetes

Fig. 4

a Effect of metformin on AMPK phosphorylation in mocks vs wild OCT-1 transfected HepG2 cells: Representative ummunoblots showing the change in pAMPK expression by the presence/absence of metformin in cells expressing vehicle control and OCT-1. The lower panel represents the effect of the same on the expression of β–actin protein used as a loading control. b Graph showing normalised densitometric values for the metformin treated and untreated mock and wild type cells

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